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http://dx.doi.org/10.1016/j.toxicon.2019.06.218 | DOI Listing |
Talanta
April 2025
Key Laboratory of Optic-electric Sensing and Analytical Chemistry for Life Science, MOE, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao, 266042, China. Electronic address:
A more efficient signal amplification strategy is needed to improve the performance of promising photoelectrochemical sensors (PEC). Organic photoelectrochemical transistor (OPECT) sensors are of growing interest in many fields, but their potential has not yet been widely exploited and remains a challenge. In this study, a novel organic photoelectrochemical transistor aptamer (OPECT) biosensor combining photoelectrochemical analysis and organic electrochemical transistor with AgI-TiO (AgI-TNs) as photoreactive material and target-specific DNA chain reaction hybridization as signal amplifier for microcystin-LR detection was developed.
View Article and Find Full Text PDFColloids Surf B Biointerfaces
February 2025
Faculdade São Leopoldo Mandic (SLMANDIC), Rua José Rocha Junqueira 13, Swift, Campinas, SP 13045-755, Brazil; Department of Comprehensive Dentistry, University of Maryland, School of Dentistry, 650 W Baltimore St., Baltimore, MD 21201, USA. Electronic address:
The objective was to address the repercussion of adding titanium dioxide nanotubes (TiO-nt) into high-viscosity conventional glass ionomer cement (GIC) on the biological properties of pre-odontoblastic cells (MDPC-23) challenged by lipopolysaccharides (LPS - 2 μg/mL). TiO-nt was added to Ketac Molar EasyMix at 3, 5, 7 %, whereas unblended GIC served as control. Analyses included proliferation (n=6; 24, 48, 72 h), metabolism (MTT; n=6; 24, 48, 72 h); morphology laser microscopy (n=3; 24, 48, 72 h); proteome assessments IL-1β, IL-6, IL-10, VEGF, TNF-α (n=3; 12, 18 h); mRNA levels (RT-PCR) of Il-1β, Il-6, Il-10, VEGF, TNF-α (n=3; 12, 18 h) and DSPP (n=3; 24, 72, 120 h).
View Article and Find Full Text PDFTalanta
March 2025
Physics Center of Minho and Porto Universities (CF-UM-UP), University of Minho, Campus de Azurém, 4800-058, Guimarães, Portugal; LaPMET - Laboratory of Physics for Materials and Emergent Technologies, University of Minho, Campus de Gualtar, 4710-057, Braga, Portugal.
Ochratoxin-A (OTA) is a widespread foodstuff contaminant with potential carcinogenic effects. Innovative sensing technologies that allow on-site and sensitive food screening can have a significant impact on food and environment safety. A novel and quantitative label-free LSPR-based biosensor was specifically designed for OTA detection, employing a portable LSPR spectroscopy sensing system for efficient on-site and cost-effective analysis.
View Article and Find Full Text PDFJ Environ Manage
December 2024
US Army Engineer Research and Development Center, Environmental Laboratory, Vicksburg, MS 39180, USA.
Adv Mater
December 2024
Department of Burns, Wound Repair & Reconstruction, Institute of Precision Medicine, The First Affiliated Hospital of Sun Yat-Sen University, Sun Yat-Sen University, Guangzhou, 510080, China.
Neutrophil extracellular traps (NETs) are web-like complexes of DNA and proteins that are extruded by activated neutrophils and play critical roles as major components of the innate immune response against pathogen invasion. However, some microbes have developed strategies to evade NET attacks, leading to impaired immune defenses and persistent infections. In this study, an engineered neutrophil strategy for enhancing the antibacterial activity of NETs is developed.
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