Neural Plast
Department of Neurobiology and Acupuncture Research, The Third Clinical College, Zhejiang Chinese Medical University, Key Laboratory of Acupuncture and Neurology of Zhejiang Province, Hangzhou 310053, China.
Published: January 2020
Our previous studies have confirmed that electroacupuncture (EA) can effectively intervene in pain memory, but the neural mechanism involved remains unclear. In this study, we observed the effects of EA in regulating pain memory-related behaviors and synchronous neural oscillations in the rostral anterior cingulate cortex (rACC). During nociceptive behavioral testing, pain memory induced a nonpain stimulus that spurred a neural oscillatory reaction similar to that caused by pain stimuli in the rACC. After EA, nonpain stimuli did not induce decreased neural oscillatory activity in the rACC until the presentation of pain stimuli. During aversive behavioral testing, EA, through the downregulation of theta power, inhibited the retrieval of aversive memory and relieved pain memory-induced aversive behaviors. These changes of oscillatory activity may be the hallmarks of EA therapy for pain memory.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541966 | PMC |
http://dx.doi.org/10.1155/2019/2057308 | DOI Listing |
Arch Clin Neuropsychol
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Department of Psychology and Brain Health Research Centre, University of Otago, 275 Leith Walk, Dunedin North, Dunedin 9016, New Zealand.
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BMC Neurol
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Graduate School of Physical Education, Myongji University, Mingzhi Road, Churen District, Yongin, 17058, Gyeonggi Province, Republic of Korea.
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Neuropsychopharmacology
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Department of Psychiatry, Oxford University, Warneford Hospital, Oxford, UK.
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View Article and Find Full Text PDFMed
January 2025
Department of Anesthesiology, Zhongshan Hospital Fudan University, Shanghai 200032, China; Laboratory of Perioperative Stress and Protection, Shanghai 200032, China. Electronic address:
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CNS Neurosci Ther
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Department of Anatomy, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan, China.
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