The authors present experimental data on the antidiabetic effect of passaged human embryonic pancreatic beta-cells in their xenotransplantation to rats with alloxan diabetes. Intra-abdominal xenotransplantation of such cultures results in a stable compensation of glycemia in rats with experimental diabetes. These data are important in terms of a possibility to use passaged human embryonic pancreatic beta-cells for transplantation to patients with diabetes mellitus.
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