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We studied immunocytochemical localization of thyrotropin-releasing (TRH) in the bullfrog pats intermedia. Many TRH-like immunoreactive terminals containing immunoreactive granular vesicles 80-150 nm in diameter (116 nm mean diameter) were found in the pars intermedia. Some TRH-like immunoreactive terminals were in synaptic contact with the intermedia cells. These findings support the hypothesis that TRH directly activates the intermedia cells via synapses to secrete alpha-melanocyte-stimulating hormone.
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| http://dx.doi.org/10.1016/0304-3940(87)90339-9 | DOI Listing |
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