The Laxity of the Native Knee: A Meta-Analysis of in Vitro Studies.

Background: Although soft-tissue balancing plays an important role in knee arthroplasty, we are aware of no objective target parameters describing the soft-tissue tension of the native knee. In the present study, we aimed to meta-analyze data from studies investigating native knee laxity to create a guide for creating a naturally balanced knee joint.

Methods: PubMed and Web of Science were searched for studies with laxity data published from 1996 through 2016. Graphs were digitally segmented in cases in which numerical data were not available in text or table form. Three-level random-effects meta-analyses were conducted.

Results: Seventy-six studies evaluating knee laxity at various flexion angles (0° to 90°) were included. Knee laxity was significantly different between 0° and 90° of flexion (p < 0.001) in all 6 testing directions, with mean differences of 0.94 mm and -0.35 mm for anterior and posterior translation, 1.61° and 4.25° for varus and valgus rotation, and 1.62° and 6.42° for internal and external rotation, respectively.

Conclusions: Knee laxity was dependent on the flexion angle of the knee joint in all degrees of freedom investigated. Furthermore, asymmetry between anterior-posterior, varus-valgus, and internal-external rotation was substantial and depended on the joint flexion angle.

Clinical Relevance: If the goal of knee arthroplasty is to restore the kinematics of the knee as well as possible, pooled laxity data of the intact soft tissue envelope could be useful as a general guide for soft-tissue balancing in total knee arthroplasty.