Following publication of the original article [1], the authors reported that name that appeared in published online version is incorrect. Aifeng Wang should be Aifen Wang. Corrected name is provided in the author group section above.
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http://dx.doi.org/10.1186/s12943-019-1034-y | DOI Listing |
PLoS One
September 2024
Department of Biosciences, Rice University, Houston, Texas, United States of America.
Neural crest cells (NCC) are multipotent migratory stem cells that originate from the neural tube during early vertebrate embryogenesis. NCCs give rise to a variety of cell types within the developing organism, including neurons and glia of the sympathetic nervous system. It has been suggested that failure in correct NCC differentiation leads to several diseases, including neuroblastoma (NB).
View Article and Find Full Text PDFInt J Mol Sci
October 2023
IRCCS Istituto Giannina Gaslini, 16147 Genova, Italy.
Chromosomal instability (CIN) induces a high rate of losses or gains of whole chromosomes or parts of chromosomes. It is a hallmark of most human cancers and one of the causes of aneuploidy and intra-tumor heterogeneity. The present study aimed to evaluate the potential prognostic role of CIN in NB patients at diagnosis.
View Article and Find Full Text PDFRadiology
June 2023
From the Departments of Radiology and Nuclear Medicine (R.W.J., C.M.d.B., S.v.E., J.A.C., R.B., M.C.d.J., P.d.G.), Human Genetics (C.J.D.), Pathology (P.v.d.V.), Oncogenetics (J.D.), and Ophthalmology (A.C.M.), Amsterdam University Medical Center, Vrije Universiteit, Office PK-1X012, De Boelelaan 1117, 1081 HV Amsterdam, the Netherlands; Cancer Center Amsterdam, Amsterdam, the Netherlands (R.W.J., C.M.d.B., S.v.E., J.D., A.C.M., M.C.d.J., P.d.G.); European Retinoblastoma Imaging Collaboration (R.W.J., C.M.d.B., L.C., S.G., P.M., H.C.B., P.G., J.A.C., M.C.d.J., P.d.G.); Imaging Department, Institut Curie Paris, Paris, France (L.C., H.J.B.); Institute of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Essen, Germany (S.G.); Impact Genetics-Dynacare, Brampton, Canada (J.L.J.); Department of Ophthalmology, Phoenix Children's Hospital, Phoenix, Ariz (A.R.); Casey Eye Institute & Knight Cancer Institute, Oregon Health & Science University, Portland, Ore (A.H.S., A.K.M.); Department of Radiology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland (P.M.); Department of Ophthalmology, Casey Eye Institute, Oregon Health & Science University, Portland, Ore (O.E.U.); Ocular Oncology Service, Emory Eye Center, Atlanta, Ga (O.E.U., G.B.H., H.G.); Department of Ophthalmology, University of Iowa Hospitals & Clinics, Iowa City, Iowa (H.C.B.); Department of Oncology, St Jude Children's Research Hospital, Memphis, Tenn (K.E.N., R.C.B.); Department of Pediatric Hematology/Oncology, Logan Health, Kalispell, Mont (R.C.B.); Department of Radiology and Imaging Sciences, Tata Medical Center, Kolkata, India (S. Sen); Department of Diagnostic Imaging, University Children's Hospital Zürich, Zürich, Switzerland (S. Sirin); and Azienda Ospedaliera Universitaria Senese, Siena, Italy (P.G.).
Background -amplified wild-type () retinoblastoma is a rare but clinically important subtype of retinoblastoma due to its aggressive character and relative resistance to typical therapeutic approaches. Because biopsy is not indicated in retinoblastoma, specific MRI features might be valuable to identify children with this genetic subtype. Purpose To define the MRI phenotype of retinoblastoma and evaluate the ability of qualitative MRI features to help identify this specific genetic subtype.
View Article and Find Full Text PDFRedox Biol
June 2023
Department of Nephrology, Shandong Provincial Hospital, Shandong University, Jinan, Shandong, 250021, China. Electronic address:
Renal fibrosis is the common histopathological feature of chronic kidney diseases (CKD), and there is increasing evidence that epigenetic regulation is involved in the occurrence and progression of renal fibrosis. N-myc downstream-regulated gene 2 (NDRG2) is significantly down-regulated in renal fibrosis, the mechanism of which remains unclear. Previous studies have confirmed that the inhibition of NDRG2 expression in tumor cells is related to hyper-methylation, mainly regulated by DNA methyltransferases (DNMTS).
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