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There should be no assumption that an athlete is immune to coronary artery disease (CAD), even when traditional cardiovascular (CV) risk factors appear well-managed. Excelling in certain aspects of health does not equate to total CV protection. Recent data from cardiac imaging studies have raised the possibility that long-term, high-volume, high-intensity endurance exercise is associated with coronary atherosclerosis.

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Predictors of coronary atherosclerosis in middle-aged and older athletes: the MARC-2 study.

Eur Heart J Cardiovasc Imaging

December 2024

Department of Medical BioSciences, Exercise Physiology Research Group, Radboud University Medical Center, Nijmegen, The Netherlands.

Aims: Exercise improves cardiovascular health, but high-volume high-intensity exercise is associated with increased coronary artery atherosclerosis and calcification (CAC). We aimed to identify predictors of CAC in athletes.

Methods And Results: We assessed the association of traditional and non-traditional cardiovascular risk factors with CAC using linear and logistic regression.

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As health systems emerge from the pandemic, academic medical centres are motivated to have a healthy and resilient workforce. In the face of the collective traumas of the pandemic, we took a systems approach to infuse wellness into our culture by modelling collective recovery in a non-traditional town hall. Over a dozen senior leaders, faculty, staff, and students shared their personal experiences in a virtual forum, nearly 1000 attendees communally supported one another.

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Article Synopsis
  • - Chronic kidney disease (CKD) is linked to an increased risk of cardiovascular disease (CVD), and as kidney function worsens, CVD prevalence, events, and mortality rates rise.
  • - Recent studies highlight the positive impact of physical activity and exercise in preventing CKD and slowing kidney function decline, while also reducing CVD risk and improving overall health.
  • - Although exercise interventions show promise for improving cardiorenal health, there's a need for more comprehensive clinical trials and better integration of these findings into patient care.
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Cardiovascular disease (CVD) poses a major health burden in adults with chronic kidney disease (CKD). While cardiorespiratory fitness, race, and sex are known to influence the relationship between CVD and mortality in the absence of kidney disease, their roles in patients with CKD remain less clear. Therefore, this narrative review aims to synthesize the existing data on CVD in CKD patients with a specific emphasis on cardiorespiratory fitness, race, and sex.

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