Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697094 | PMC |
| http://dx.doi.org/10.1056/NEJMp1905589 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Discovery, Characterization, and Application of Broad-Spectrum Antimicrobial Peptide AtR905 from as a Biocontrol Agent.
J Agric Food Chem
December 2024
Key Laboratory of Microbial Pesticides (Ministry of Agriculture and Rural Affairs), National Biopesticide Engineering Research Centre, Hubei Biopesticide Engineering Research Centre, Hubei Academy of Agricultural Sciences, Wuhan 430064, China.
This study investigates a novel antimicrobial peptide AtR905 derived from the endophytic fungus , which was successfully expressed in , purified, and characterized, and highlighted as a promising potential biocontrol agent against various plant pathogens. The results indicated AtR905 exhibited broad-spectrum antimicrobial activities against key pathogens such as and with very low minimal inhibitory concentrations (MICs). Stability tests confirmed that AtR905 retains its antimicrobial properties under varying thermal, pH, and UV conditions.
View Article and Find Full Text PDFPolyethylene terephthalate nanoplastics affect potassium accumulation in foxtail millet (Setaria italica) seedlings.
BMC Plant Biol
December 2024
School of Life Science, Shanxi University, Taiyuan, 030006, Shanxi, China.
Background: As modern industrial activities have advanced, the prevalence of microplastics and nanoplastics in the environment has increased, thereby impacting plant growth. Potassium is one of the most crucial nutrient cations for plant biology. Understanding how polyethylene terephthalate (PET) treatment affects potassium uptake will deepen our understanding of plant response mechanisms to plastic pollution.
View Article and Find Full Text PDFA review on comparative analysis of marine and freshwater fish gut microbiomes: insights into environmental impact on gut microbiota.
FEMS Microbiol Ecol
December 2024
Department of Animal Sciences, School of Life Sciences, Central University of Himachal Pradesh, Dharamshala, Himachal Pradesh 176206, India.
The gut microbiota, which includes prokaryotes, archaea, and eukaryotes like yeasts, some protozoa, and fungi, significantly impact fish by affecting digestion, metabolism, and the immune system. In this research, we combine various tasks carried out by various bacteria in the gut of fish. This study also examines the gut microbiome composition of marine and freshwater fish, identifying important bacterial species linked to different biological functions.
View Article and Find Full Text PDFEthical bioprospecting and microbial assessments for sustainable solutions to the AMR crisis.
IUBMB Life
January 2025
Centre to Impact AMR, Monash University, Melbourne, Australia.
Antimicrobial resistance (AMR) has been declared one of the top 10 global public health challenges of our age by the World Health Organization, and the World Bank describes AMR as a crisis affecting the finance, health, and agriculture sectors and a major threat to the attainment of Sustainable Development Goals. But what is AMR? It is a phenotype that evolves in microbes exposed to antimicrobial molecules and causes dangerous infections. This suggests that scientists and healthcare workers should be on the frontline in the search for sustainable solutions to AMR.
View Article and Find Full Text PDFCase report: A novel third-generation anti-CD19/CD22 CAR T-cells combined with auto-HSCT for relapsed Burkitt lymphoma.
Front Immunol
December 2024
The Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
This study explores a novel therapeutic strategy for relapsed/refractory (R/R) Burkitt lymphoma (BL) by integrating autologous hematopoietic stem cell transplantation (ASCT) with tandem anti-CD19/CD22 chimeric antigen receptor (CAR) T cell therapy. A 20-year-old Asian male with refractory BL, whose lymphoma had not responded to multiple chemoimmunotherapy regimens, received myeloablative ASCT followed three days later by infusion of a novel third-generation CAR T cells engineered with CD28 and CD3ζ signaling domains, along with a TLR2 costimulatory domain. This resulted in sustained complete remission at the 306-day follow-up, without experiencing any severe complications.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!