Introduction: The explosion of mobile phone users along with the importance of user's role in managing their health provides a unique opportunity for m-Health applications in the management of chronic illnesses such as Multiple sclerosis (MS).
Aim: To identify available MS applications and to characterize the content of MS self-management applications.
Methods: Two popular online application stores (iTunes, Google play) were searched for multiple sclerosis -related apps using the following keywords: multiple sclerosis, disseminated multiple sclerosis, disseminated sclerosis, and MS. Apps were considered eligible if they had been customized only on multiple sclerosis. First, data was extracted from the description page for any eligible application. To achieve the study goal, the secondary analysis was performed only for self-management applications.
Results: Search of two popular markets identified 1042 applications (747 applications from Google play, and 295 applications from iTunes). Of these, 104 unique applications met the inclusion criteria. Almost a quarter of eligible applications (26%) had been designed for multiple sclerosis self-management. Other purposes of the identified applications were diagnosing & treating (7.7%), doing tests (7.7%), connecting & communication for MS patients (4.8%), raising awareness of multiple sclerosis (15.4%), accessing to journals & news (6.7%), conferences & meetings (17.3%), supporting & donating to MS community (14.4%).
Conclusion: It appears the mobile applications provide a multidimensional tool for patient with Multiple Sclerosis to improve their condition self-management. These applications can contribute to empowerment of the patients, and help their adherence to the therapeutic and management regimen of their conditions. Moreover, they can be utilized to collect information on the MS progress pattern in personal level for each individual patient. This information may provide health care professionals with evidence to help their patients toward enhancing self-management of their disease.
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http://dx.doi.org/10.5455/aim.2019.27.12-18 | DOI Listing |
Immunology
January 2025
Department of Neurology, Xuanwu Hospital Capital Medical University, Beijing, China.
Platelets and neutrophils are among the most abundant cell types in peripheral blood. Beyond their traditional roles in thrombosis and haemostasis, they also play an active role in modulating immune responses. Current knowledge on the role of platelet-neutrophil interactions in the immune system has been rapidly expanding.
View Article and Find Full Text PDFAnn Neurol
January 2025
Neuroimaging Research Unit, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Objective: The aim of this study was to explore the microstructural dynamics of the subventricular zone (SVZ) with aging and their associations with clinical disability and brain structural damage in pediatric-onset multiple sclerosis (MS) patients.
Methods: One-hundred and forty-one pediatric-onset MS patients (67 pediatric and 74 adults with pediatric-onset) and 233 healthy controls (HC) underwent neurological and 3.0 T MRI assessment.
Mult Scler
January 2025
Center for Multiple Sclerosis and Autoimmune Neurology, Mayo Clinic, Rochester, MN, USA.
Background: Spinal cord (SC) atrophy is a key imaging biomarker of progressive multiple sclerosis (MS). Progressive MS is more common in men and postmenopausal women.
Objective: Investigate the impact of sex and menopause on SC measurements in persons with MS (pwMS).
FEBS Open Bio
January 2025
Sunny BioDiscovery Inc., Santa Paula, CA, USA.
Dimethyl fumarate (DMF) is an anti-inflammatory and immunoregulatory medication used to treat multiple sclerosis (MS) and psoriasis. Its skin sensitization property precludes its topical use, which is unfortunate for the treatment of psoriasis. Isosorbide di-(methyl fumarate) (IDMF), a novel derivative of DMF, was synthesized to circumvent this adverse reaction and unlock the potential of topical delivery, which could be useful for treating psoriasis in the subpopulation of psoriatic MS patients, as well as in the general population.
View Article and Find Full Text PDFHum Genomics
January 2025
Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Richards Building B304, 3700 Hamilton Walk, Philadelphia, PA, 19104, USA.
Background: Disease comorbidities and longer-term complications, arising from biologically related associations across phenotypes, can lead to increased risk of severe health outcomes. Given that many diseases exhibit sex-specific differences in their genetics, our objective was to determine whether genotype-by-sex (GxS) interactions similarly influence cross-phenotype associations. Through comparison of sex-stratified disease-disease networks (DDNs)-where nodes represent diseases and edges represent their relationships-we investigate sex differences in patterns of polygenicity and pleiotropy between diseases.
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