Objectives: To evaluate sensitivity, specificity and accuracy of Magnetic Resonance Imaging (MRI) in diagnosis and assessment the depth of invasion of placenta accreta (PA) in high risk gravid women.
Materials & Methods: The study included 58 pregnant women with multiple risk factors for PA. Placental mapping by ultrasound was followed by MRI when the patients were diagnosed or suspicious by ultrasound to have PA. Focal myometrial interruption, dark intra-placental band, heterogeneous placenta, focal uterine bulge and invasion to the surrounding organs were used as a sign of diagnosis of PA. The results of the MRI were compared with intraoperative findings and/or histopathological diagnosis.
Results: Placenta Previa was detected at MRI in 58 cases and PA in 49 cases. The sensitivity, specificity and accuracy of MRI in the diagnosis of PA were (100%, 75%, and 94.8% respectively) and (100%, 42.8%, and 79.3% respectively) in assessing the depth of invasion. Invasion to the surrounding organs sign was the most reliable sign in diagnosis of placenta percreta.
Conclusion: MRI is a reliable method in the diagnosis of PAbut less reliable in assessing the depth of invasion of placenta accreta and increta making the task of differentiating between them difficult. Placenta percreta diagnosed accurately by invasion to the surrounding organs.
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http://dx.doi.org/10.1016/j.clinimag.2019.05.003 | DOI Listing |
J Dev Behav Pediatr
January 2025
Department of Paediatrics, The University of Melbourne, Melbourne, Australia.
Objective: Wearable technology has potential benefits for clinical measurement with children who have neurodevelopmental disorders (NDDs). However, this cohort may experience sensory processing disorder, behavioral dysregulation, and cognitive challenges. For effective and considerate implementation, the experiences and views of parents of children with NDDs on this topic need in-depth investigation.
View Article and Find Full Text PDFJ Cell Mol Med
January 2025
Department of Gastroenterology, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, Zhejiang Province, China.
Trophoblast glycoprotein (TPBG) plays a significant part in the growth of specific cancers, yet its connection to gastric cancer (GC) remains uncertain. This research seeks to analyse the fluctuation in TPBG levels in GC and evaluate how TPBG expression relates to the prognosis of GC patients. TPBG expression in GC and normal gastric tissues was investigated in The Cancer Genome Atlas (TCGA) and Genotype-Tissue Expression (GTEx) database, further extracting the immunohistochemistry images from HPA database and validating by Western blot.
View Article and Find Full Text PDFAnn Surg Treat Res
January 2025
Department of Surgery, Chonnam National University Hwasun Hospital, Chonnam National University Medical School, Hwasun, Korea.
Purpose: Determining the extent of radical lymphadenectomy at clinical early stage is challenging. We aimed to investigate the appropriate extent of lymphadenectomy in clinical early-stage right colon cancer.
Methods: Patients with clinical stage 0 or I right colon cancer who underwent curative surgery from January 2007 to December 2021 were included in this retrospective study.
Adv Healthc Mater
January 2025
Department of Chemical and Biomolecular Engineering, University of Notre Dame, Notre Dame, IN, 46556, USA.
Aging is one of the most significant risk factors for breast cancer. With the growing interest in the alterations of the aging breast tissue microenvironment, it is identified that aging is related to tumorigenesis, invasion, and drug resistance. However, current pre-clinical disease models often neglect the impact of aging and sometimes result in worse clinical outcomes.
View Article and Find Full Text PDFJ Burn Care Res
January 2025
US Army Institute of Surgical Research, JBSA Ft Sam Houston, TX, US.
Two randomized controlled trials conducted in acutely burned patients found clinical benefits with higher carbohydrate (60-65% of total energy), lower fat (12-15%) nutrition, to include faster wound healing, fewer wound infections, decreased hospital stay, and less pneumonia. The primary purpose of this study was to assess whether our change in practice to a higher proportion of carbohydrates (60%) with 25% of energy from protein, and 15% of energy from fat was associated with improved wound healing rates. Secondary outcomes evaluated included invasive fungal wound infections, ischemic bowel, sepsis, and mortality.
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