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Low-grade infections in nonunion of the femur and tibia without clinical suspicion of infection - Incidence, microbiology, treatment, and outcome.
Injury
January 2025
Institute for Biomechanics, Paracelsus Medical University, Strubergasse 21, 5020 Salzburg, Austria; Department of Trauma Surgery, BG Unfallklinik Murnau, Professor-Küntscher-Str. 8, 82418 Murnau am Staffelsee, Germany.
Treatment algorithms for fracture nonunion depend on the presence or absence of bacterial infection. However, it is often impossible to identify infection preoperatively. While some infections may present with clinical signs of infection, low-grade infections lack infection signs and have a clinical presentation similar to aseptic nonunion.
View Article and Find Full Text PDFKampo medicine inducing drug-induced liver injury: A case report and systematic review.
Drug Discov Ther
January 2025
Department of Hospital Pharmaceutics, School of Pharmacy, Showa University, Tokyo, Japan.
Article Synopsis
- Kampo medicine can lead to severe liver injury, as shown in a case where a 29-year-old woman experienced this after taking Saibokuto, requiring steroid treatment for recovery.
- A systematic review identified 37 cases of drug-induced liver injury linked to Kampo medicines, with 65.9% specifically associated with the ingredient Scutellariae radix.
- The findings suggest important liver function monitoring within the first two months of taking Kampo medicines with Scutellariae radix due to the potential for liver damage.
Ethical Use of Cadaveric Images in Anatomical Textbooks, Atlases, and Journals: A Consensus Response From Authors and Editors.
Clin Anat
January 2025
Department of Neurosurgery, Tulane University School of Medicine, New Orleans, Louisiana, USA.
Nowadays, consent to use donor bodies for medical education and research is obtained from the body donors and their families before the donation. Recently, the International Federation of Associations of Anatomists (IFAA) published guidelines that could restrict the appearance of cadaveric images in commercial anatomical resources such as textbooks and other educational products. These guidelines state that the donor must expressly consent to using such images for this purpose.
View Article and Find Full Text PDFA xenogenic-free culture medium for cell micro-patterning systems as cell-instructive biomaterials for potential clinical applications.
Biomed Mater
December 2024
G.E.R.N. Research Center for Tissue Replacement, Regeneration & Neogenesis; Department of Orthopedics and Trauma Surgery, Faculty of Medicine, Medical Center-Albert-Ludwigs-University of Freiburg, Engesserstr. 4, Freiburg im Breisgau, 79108, GERMANY.
Cell micro-patterning controls cell fate and function and has potential for generating therapeutically usable mesenchymal stromal cell (MSC) populations with precise functions. However, to date, the micro-patterning of human cells in a translational context has been impossible because only ruminant media supplements, e.g.
View Article and Find Full Text PDFUnpacking Indigenous Social Mobility: Entrepreneurs, Social Networks, and Connections to Culture.
Bus Soc
January 2025
The University of Melbourne, VIC, Australia.
In settler societies, upward social mobility by Indigenous people is seen in the growth of successful professional and entrepreneurial classes where both wealth creation and social power are significant resources. Yet, public and academic discourses perpetuate the belief that social mobility impacts negatively on Indigenous people by placing cultural identity in conflict with capitalist business practices. Using data from an international comparison consisting of interviews with 220 Indigenous entrepreneurs in research sites across three countries, this article shows that the belief is unfounded and reveals how this duality creates an impossible tension when Indigenous cultural identity is framed as "at risk" because of social mobility.
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