AI Article Synopsis

  • - A healthy toddler was treated for gastroenteritis that also led to encephalopathy and liver inflammation (hepatitis).
  • - Testing revealed the presence of human herpesvirus 6 (HHV-6) using a specialized meningitis panel.
  • - Additional testing confirmed a likely diagnosis of a first-time (primary) infection with HHV-6B.

Article Abstract

An immunocompetent toddler came to medication attention with gastroenteritis, complicated by encephalopathy and hepatitis. Multiplexed testing using a polymerase chain reaction meningitis panel was positive for human herpesvirus 6 (HHV-6). Clinical correlation, quantitative HHV-6 polymerase chain reaction, and metagenomic next-generation sequencing supported a likely diagnosis of primary HHV-6B infection.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707859PMC
http://dx.doi.org/10.1016/j.jpeds.2019.04.058DOI Listing

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