Historic cell culture media were designed to ensure continuous cancer cell proliferation in vitro. However, their composition does not recapitulate the nutritional environment of the tumor. Recent studies show that novel media formulations alleviate the nonphysiological constraints imposed by historic media, and lead to cell culture results that are more relevant to tumor metabolism.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557711 | PMC |
| http://dx.doi.org/10.1016/j.trecan.2019.05.004 | DOI Listing |
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