The effect of food waste (FW) co-digestion with wastewater biosolids (WWB) on microbial communities was investigated through running thirteen lab-scale digesters for 100 days at different operational conditions i.e. organic loading rates (2 and 4 kgCOD/m·day), feed types (WWB and FW), and FW content (10%, 90%, 100%). Compared with mono-digestion of WWB, FW co-digestion enhanced biogas production by 13% and COD degradation rates by up to 101%. Among fermentative bacteria/acetogens, Syntrophomonas was the dominant genus in FW digesters in contrast to the dominance of Clostridium in WWB digesters. The predominant methanogen was Methanosarcina in FW digesters in contrast to Methanosaeta in WWB digesters. COD degradation rates and methane yields were well correlated with Bacteroidetes population. Methane production rate was well correlated with Clostridium for FW digesters, with syntrophs for WWB digesters, and with aceticlastic methanogens for both digesters. Synergism was associated with hydrolytic bacteria, Clostridium, Syntrophomonas, syntrophs, Methanosarcina, and Methanobacterium.
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http://dx.doi.org/10.1016/j.biortech.2019.121580 | DOI Listing |
Biomed Mater
November 2024
Core Labs, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi Arabia.
This study aimed to optimize mesalamine (MES)-nanoparticles (NPs) using Box Behnken Design and investigate itsantioxidant potential in colon drug targeting. The formulation was prepared using oil/water (O/W) emulsion solvent evaporation technique for time dependent colonic delivery. The optimal formulation with the following parameters composition was selected: polymer concentration (% w/w) (A) = 0.
View Article and Find Full Text PDFBiochim Biophys Acta Rev Cancer
November 2024
Department of General Surgery, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100023, PR China; Key Laboratory of Research in Pancreatic Tumor, Chinese Academy of Medical Sciences, Beijing 100023, PR China; National Science and Technology Key Infrastructure on Translational Medicine in Peking Union Medical College Hospital, Beijing 100023, PR China. Electronic address:
Cell Mol Life Sci
September 2021
Department of General Surgery, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China.
Pancreatic cancer (PC) is a kind of common digestive system cancer with the worst prognosis for its insidious symptoms and high invasiveness. Circular RNAs (circRNAs) are endogenous non-coding RNAs with covalently closed circular structure, which are more stable and conservative than linear RNAs and process major functions of microRNA (miRNA) sponge, RNA binding protein (RBP) sponge and polypeptide translation template. Incremental researches have proved that circRNAs express aberrantly and play a vital role in various types of cancer.
View Article and Find Full Text PDFInt J Clin Oncol
February 2021
Department of International Medical Services, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
Background And Objective: Small bowel adenocarcinoma (SBA) is a rare malignant tumor with a poor prognosis. Most patients with SBA are diagnosed with advanced-stage disease. Due to the lack of randomized controlled trials and prospective studies, it is difficult to predict the prognosis of patients with SBA.
View Article and Find Full Text PDFWorld J Gastroenterol
August 2019
Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences/Peking Union Medical College, Beijing 100730, China.
Zollinger-Ellison syndrome (ZES) is characterized by gastric acid hypersecretion causing severe recurrent acid-related peptic disease. Excessive secretion of gastrin can now be effectively controlled with powerful proton pump inhibitors, but surgical management to control gastrinoma itself remains controversial. Based on a thorough literature review, we design a surgical algorithm for ZES and list some significant consensus findings and recommendations: (1) For sporadic ZES, surgery should be routinely undertaken as early as possible not only for patients with a precisely localized diagnosis but also for those with negative imaging findings.
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