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Uganda is currently implementing the Global Health Security Agenda (GHSA), aiming at accelerating compliance to the International Health Regulations (IHR) (2005). To assess progress toward compliance, a Joint External Evaluation (JEE) was conducted by the World Health Organization (WHO). Based on this evaluation, we present the process and lessons learned. Uganda's methodological approach to the JEE followed the WHO recommendations, including conducting a whole-of-government in-country self-assessment prior to the final assessment, using the same tool at both assessments, and generating consensus scores during the final assessment. The in-country self-assessment process began on March 24, 2017, with a multisectoral representation of 203 subject matter experts from 81 institutions. The final assessment was conducted between June 26 and 30, 2017, by 15 external evaluators. Discrepancies between the in-country and final scores occurred in 27 of 50 indicators. Prioritized gaps from the JEE formed the basis of the National Action Plan for Health Security. We learned 4 major lessons from this process: subject matter experts should be adequately oriented on the scoring requirements of the JEE tool; whole-of-government representation should be ensured during the entire JEE process; equitable multisectoral implementation of IHR activities must be ensured; and over-reliance on external support is a threat to sustainability of GHSA gains.
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http://dx.doi.org/10.1089/hs.2018.0137 | DOI Listing |
Front Cardiovasc Med
December 2024
Seattle Children's Hospital, Seattle, WA, United States.
Introduction: The use of cardiopulmonary bypass (CPB) can induce sterile systemic inflammation that contributes to morbidity and mortality, especially in children. Patients have been found to have increased expression of cytokines and transmigration of leukocytes during and after CPB. Previous work has demonstrated that the supraphysiologic shear stresses existing during CPB are sufficient to induce proinflammatory behavior in non-adherent monocytes.
View Article and Find Full Text PDFFront Psychol
December 2024
Sustainable Energy and Climate Policies Research Centre (SENLAB), Izmir University of Economics, Izmir, Türkiye.
Interventions aiming at behavioral change are common tools for assessing and stimulating environmentally friendly lifestyles. To obtain representative and scalable results from the interventions, the experimental design of the interventions is crucial. Likewise, an operational plan is significant concerning the coherence and consistency of the interventions and the comparability of the results from different interventions.
View Article and Find Full Text PDFFront Psychol
December 2024
Department of Applied Social Sciences, The Hong Kong Polytechnic University, Kowloon, Hong Kong SAR, China.
Introduction: There is a notable scarcity of research examining the developmental trajectories of positive youth development (PYD) attributes among Chinese preadolescents and adolescents and the predictive effect of family functioning on these trajectories over time.
Methods: Using four waves of data, this longitudinal study investigated preadolescents and adolescents in China in January 2020 (T1), June 2020 (T2), June 2021 (T3), and June 2022 (T4). The study utilized the 90-item "Chinese Positive Youth Development Scale" and the 33-item "Chinese Family Assessment Instrument" to assess PYD and family functioning, respectively.
Front Allergy
December 2024
Allergy Department, Castellon University General Hospital, Castellon de la Plana, Spain.
Background: Hypersensitivity reactions to chemotherapy disrupt treatment schedules and compromise patient outcomes. Rapid Drug Desensitization (RDD) enables patients to tolerate future treatments after an allergy workup. However, Same-Day Desensitization (SDD) is a novel approach that capitalizes on RDD to allow the continuation of chemotherapy on the same day as the index reaction, preventing treatment delays.
View Article and Find Full Text PDFCureus
November 2024
Ali-Ul-Murtaza, Department of Rehabilitation Sciences, Muhammad Institute of Medical and Allied Sciences, Multan, PAK.
Background Given the increasing incidence and severity of knee osteoarthritis (OA), it is crucial to investigate and refine therapeutic approaches. Aim The objective of this study is to evaluate the effectiveness and potential synergistic effects of proprioceptive exercises combined with Mulligan traction straight leg raise (MT-SLR) in treating OA. This includes improving symptoms such as functional mobility, pain reduction, and relevant serological markers, highlighting the potential of this approach to enhance overall patient outcomes.
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