In order to reduce the complexity of heart hemodynamics simulations, uncoupling approaches are often considered for the modeling of the immersed valves as an alternative to complex fluid-structure interaction (FSI) models. A possible shortcoming of these simplified approaches is the difficulty to correctly capture the pressure dynamics during the isovolumetric phases. In this work, we propose an enhanced resistive immersed surfaces (RIS) model of cardiac valves, which overcomes this issue. The benefits of the model are investigated and tested in blood flow simulations of the left heart where the physiological behavior of the intracavity pressure during the isovolumetric phases is recovered without using fully coupled fluid-structure models and without important alteration of the associated velocity field.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/cnm.3223 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Ultrasonographic assessment of the fetal heart in intrahepatic cholestasis of pregnancy: Pulsed wave Doppler, M-mode, and tissue Doppler imaging prospective study.
Int J Gynaecol Obstet
February 2025
Department of Obstetrics and Gynecology, Ministry of Health, Ankara City Hospital, University of Health Sciences, Ankara, Türkiye.
Objectives: To investigate the fetal heart using pulsed wave Doppler, M-mode, and tissue Doppler imaging (TDI) in cases of intrahepatic cholestasis of pregnancy (ICP).
Methods: This prospective study was conducted at a single tertiary center and included 35 patients with ICP and 70 healthy pregnant women at 28-36 weeks of pregnancy. Among the patients with ICP, 26 had serum bile acid (SBA) levels less than 40 μmol/L and nine had SBA levels of 40 μmol/L or greater.
Ivabradine in Septic Shock: A Narrative Review.
J Clin Med
April 2024
Department of Intensive Care, Hôpital Erasme, Université Libre de Bruxelles, 1070 Brussels, Belgium.
In patients with septic shock, compensatory tachycardia initially serves to maintain adequate cardiac output and tissue oxygenation but may persist despite appropriate fluid and vasopressor resuscitation. This sustained elevation in heart rate and altered heart rate variability, indicative of autonomic dysfunction, is a well-established independent predictor of adverse outcomes in critical illness. Elevated heart rate exacerbates myocardial oxygen demand, reduces ventricular filling time, compromises coronary perfusion during diastole, and impairs the isovolumetric relaxation phase of the cardiac cycle, contributing to ventricular-arterial decoupling.
View Article and Find Full Text PDFEvaluation of left ventricular flow field changes after stress in patients with nonobstructive coronary artery disease using ultrasonic flow vector imaging.
Front Cardiovasc Med
March 2024
Department of Cardiovascular Ultrasound and Cardiac Function, Affiliated Hospital of University of Electronic Science and Technology, Sichuan Provincial People's Hospital Sichuan Provincial Key Laboratory of Ultrasonic Cardiac Electrophysiology and Biomechanics Sichuan Clinical Medical Research Center for Cardiovascular Disease National Clinical Medical Research Center for Cardiovascular Diseases Branch Center, Chengdu, China.
Purpose: Vector flow mapping and treadmill exercise stress echocardiography were used to evaluate and explore changes in the left ventricular (LV) flow field of patients with nonobstructive coronary artery disease.
Methods: Overall, 34 patients with nonobstructive (<50%) left anterior descending coronary artery stenosis (case group) and 36 patients with no coronary artery stenosis (control group) were included. Apical four-, three-, and two-chamber echocardiographic images were collected at rest and during early recovery from treadmill exercise.
Modeling isovolumetric phases in cardiac flows by an Augmented Resistive Immersed Implicit Surface method.
Int J Numer Method Biomed Eng
December 2023
MOX, Laboratory of Modeling and Scientific Computing, Dipartimento di Matematica, Politecnico di Milano, Milan, Italy.
A major challenge in the computational fluid dynamics modeling of the heart function is the simulation of isovolumetric phases when the hemodynamics problem is driven by a prescribed boundary displacement. During such phases, both atrioventricular and semilunar valves are closed: consequently, the ventricular pressure may not be uniquely defined, and spurious oscillations may arise in numerical simulations. These oscillations can strongly affect valve dynamics models driven by the blood flow, making unlikely to recovering physiological dynamics.
View Article and Find Full Text PDFBackground: Some women experience voiding dysfunction after stress urinary incontinence (SUI) surgery. We explore if detrusor underactivity (DU) found in urodynamic study (UDS) prior to SUI surgery using an adjustable single incision sling (SIS) may be related to voiding dysfunction after surgery.
Methods: This is a prospective, diagnostic, transversal, single center study comparing voiding dysfunction after SUI surgery with a SIS (Altis; Coloplast, Humlebæk, Denmark) between women with DU (cases) or normal detrusor (controls).
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!