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Trends in the epidemiology of intravascular device-associated bacteremia among French hematology patients: insights from the SPIADI prospective multicenter study, 2020-2024.
Ann Hematol
January 2025
Mission Nationale Surveillance et Prévention des Infections Associées aux Dispositifs Invasifs (SPIADI), Centre d'Appui pour la Prévention des Infections Associées aux Soins en région Centre val de Loire, Centre Hospitalier Régional Universitaire, Hôpital Bretonneau, Tours, France.
Hematology patients require central venous catheters for cancer treatment and nutrition, which increases their risk of intravascular device-associated bacteremia. In the absence of recent data, we investigated intravascular device-associated bacteremia in this specific context. A three-month surveillance was conducted annually in 27 hematology wards, using a protocol derived from the HAI-Net ICU ECDC protocol (2020-2024).
View Article and Find Full Text PDFFirst out-of-bed mobilisation in adults with severe acquired brain injury in Scandinavian neurointensive care units: A survey of current clinical practice (FOOBScan).
Acta Anaesthesiol Scand
February 2025
Department of Brain and Spinal Cord Injury, Neuroscience Centre, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Background: The harm-benefit balance for early out-of-bed mobilisation of patients with severe acquired brain injury (ABI) in neurointensive care units (neuro-ICUs) is unclear, and there are no clinical guidelines. This study aimed to survey the current clinical practice and perceptions among clinicians involved in first out-of-bed mobilisation in Scandinavian neuro-ICUs.
Methods: This was a cross-sectional, anonymous, web-based survey; the reporting follows the recommended CROSS checklist.
Gynecological gender-affirming surgeries: what are the motivations and experiences? A qualitative study.
J Sex Med
January 2025
Department of Obstetrics and Gynaecology, Amsterdam UMC, location Vrije Universiteit Amsterdam, Amsterdam 1018HV, The Netherlands.
Background: Although many transmasculine individuals undergo 1 or more gynecological surgeries (ie, hysterectomy, oophorectomy, tubectomy, or colpectomy), little has been published about motivation, subjective experiences, and the effect on dysphoria and quality of life.
Aim: The aim of this study was to acquire an in-depth understanding of patients' motivations and experienced outcomes of gynecological gender surgery.
Methods: In this qualitative study, in-depth semi-structured interviews were conducted.
Biomarkers.
Alzheimers Dement
December 2024
Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA.
Background: Glymphatic clearance dysfunction within the perivascular space has been implicated in Alzheimer's Disease (AD) pathology. Diffusion MRI-based techniques such as DTI-ALPS can quantify perivascular interstitial fluid (ISF) dynamics, yet their links with other early AD markers in the cognitively normal elderly population remain underexplored. Here, we investigated associations between DTI-ALPS and cerebral β-amyloid (Aβ) burden measured with Pittsburgh Compound B (PiB)-PET.
View Article and Find Full Text PDFBiomarkers.
Alzheimers Dement
December 2024
Pacific Brain Health Center, Pacific Neuroscience Institute and Foundation, Santa Monica, CA, USA.
Background: Brain aging (BA) involves the gradual deterioration of brain systems and is associated with chronological age (CA). Measures of BA have been validated and adopted in aging and neurological disease research (Biondo, 2022; Eickhoff, 2021) and could be a useful clinical tool. BA predicts CA in healthy adults (Cole, 2017) and accelerated BA precede Alzheimer's disease (AD) symptoms (Elliott, 2021).
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