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Automatic segmentation of white matter lesions on multi-parametric MRI: convolutional neural network versus vision transformer.
BMC Neurol
January 2025
Department of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, School of Medicine, College of Medicine, National Sun Yat-Sen University, No. 123 Ta-Pei Road, Niao-Sung Dist, Kaohsiung, 83305, Taiwan.
Background And Purpose: White matter hyperintensities in brain MRI are key indicators of various neurological conditions, and their accurate segmentation is essential for assessing disease progression. This study aims to evaluate the performance of a 3D convolutional neural network and a 3D Transformer-based model for white matter hyperintensities segmentation, focusing on their efficacy with limited datasets and similar computational resources.
Materials And Methods: We implemented a convolution-based model (3D ResNet-50 U-Net with spatial and channel squeeze & excitation) and a Transformer-based model (3D Swin Transformer with a convolutional stem).
One-week test-retest recordings of resting cardiorespiratory data for reliability analysis.
Sci Data
January 2025
Lab for Autonomic Neuroscience, Imaging and Cognition (LANIC), Department of Psychosomatic Medicine and Psychotherapy, Jena University Hospital, Jena, Germany.
Heart rate variability (HRV) is a key indicator of cardiac autonomic function, making reliable assessment crucial. To examine the test-retest stability of resting HRV in healthy individuals, fifty participants attended two lab sessions within a week, at the same time of day. After a 5-minute acclimatization period, electrocardiogram and respiration were recorded at rest.
View Article and Find Full Text PDFSerum Biomarkers in Transthyretin Amyloidosis: An Overview of Neurofilaments, Cardiac, Renal, and Gastrointestinal Involvement.
Neurol Ther
January 2025
Department of Neuroscience, Università Cattolica del Sacro Cuore, Rome, Italy.
Hereditary transthyretin amyloidosis (ATTRv, v for variant) is a genetic disorder characterized by the deposition of misfolded transthyretin (TTR) protein in tissues, resulting in progressive dysfunction of multiple organs, including the nervous system, heart, kidneys, and gastrointestinal (GI) tract. Noninvasive serum biomarkers have become key tools for diagnosing and monitoring ATTRv. This review examines the role of available biomarkers for neurological, cardiac, renal, gastrointestinal, and multisystemic involvement in ATTRv.
View Article and Find Full Text PDFGod Knows Best: Exploring the God Locus of Health Control, Race-Ethnicity, and Risk-Taking and Protective Behaviors Interrelationship in the USA.
J Relig Health
January 2025
Department of Sociology and Demography, The University of Texas at San Antoni, San Antonio, TX, USA.
The health implications of engaging in risk-taking or protective behaviors can have long-lasting effects on an individual's life. In recent years, there has been a growing interest in how religious attitudes and beliefs influence an individual's health behaviors. However, research on the role of the God Locus of Health Control (GLHC) in the religion-health literature is lacking.
View Article and Find Full Text PDFEffect of catalase on CPC production during fermentation of Acremonium chrysogenum.
Bioresour Bioprocess
January 2025
Qingdao Innovation Institute of East China University of Science and Technology, State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, People's Republic of China.
Cephalosporin C (CPC) is a critical raw material for cephalosporin antibiotics produced by Acremonium chrysogenum. During fermentation, the oxygen supply is a crucial factor limiting the efficient biosynthesis of CPC. This study demonstrated that the addition of exogenous surfactants significantly increased the dissolved oxygen (DO) level, extracellular catalase content, and final CPC titer.
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