Background: The role of governance in strengthening tuberculosis (TB) control has received little research attention. This review provides evidence of how institutional designs and organisational practices influence implementation of the national TB control programme (NTP) in Nigeria.
Main Text: We conducted a scoping review using a five-stage framework to review published and grey literature in English, on implementation of Nigeria's NTP and identified themes related to governance using a health system governance framework. We included articles, of all study designs and methods, which described or analysed the processes of implementing TB control based on relevance to the research question. The review shows a dearth of studies which examined the role of governance in TB control in Nigeria. Although costed plans and policy coordination framework exist, public spending on TB control is low. While stakeholders' involvement in TB control is increasing, institutional capacity is limited, especially in the private sector. TB-specific legislation is absent. Deployment and transfer of staff to the NTP are not transparent. Health workers are not transparent in communicating service entitlements to users. Despite existence of supportive policies, integration of TB control into the community and general health services have been weak. Willingness to pay for TB services is high, however, transaction cost and stigma among patients limit equity. Effectiveness and efficiency of the NTP was hindered by inadequate human resources, dilapidated service delivery infrastructure and weak drug supply system. Despite adhering to standardized recording and reporting format, regular monitoring and evaluation, revision of reporting formats, and electronic data management system, TB surveillance system was found to be weak. Delay in TB diagnosis and initiation of care, poor staff attitude to patients, lack of privacy, poor management of drug reactions and absence of infection control measures breach ethical standards for TB care.
Conclusions: This scoping review of governance of TB control in Nigeria highlights two main issues. Governance for strengthening TB control programmes in low-resource, high TB burden settings like Nigeria, is imperative. Secondly, there is a need for empirical studies involving detailed analysis of different dimensions of governance of TB control.
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http://dx.doi.org/10.1186/s40249-019-0556-2 | DOI Listing |
Clin Sci (Lond)
January 2025
Center for Interdisciplinary Research in Biology, College de France, Institut National de la Santé et de la Recherche Médicale, Paris, France.
Apelin, a (neuro) vasoactive peptide, plays a prominent role in controlling water balance and cardiovascular functions. Apelin and its receptor co-localize with vasopressin in magnocellular vasopressinergic neurons. Apelin receptors (Apelin-Rs) are also expressed in the collecting ducts of the kidney, where vasopressin type 2 receptors are also present.
View Article and Find Full Text PDFBiomacromolecules
January 2025
Université de Pau et des Pays de l'Adour, CNRS, UMR 5254, IPREM, 2 av. P. Angot, Pau, Pau F-64053, France.
Terpene-based amphiphilic copolymers have been designed as biobased stabilizers for waterborne latex synthesized by miniemulsion or emulsion polymerization of 1,3-diene terpene monomers. The pH-responsive P(AA--My) amphiphilic copolymers were synthesized by nitroxide-mediated radical copolymerization of β-myrcene (My) and acrylic acid (AA) with reactivity ratios of = 0.24 ± 0.
View Article and Find Full Text PDFLangmuir
January 2025
Institute of Chemical Technology and Engineering, Faculty of Chemical Technology, Poznan University of Technology, ul. Berdychowo 4, PL 60-965 Poznan, Poland.
Despite extensive research on the use of salts to enhance micellar growth, numerous questions remain regarding the impact of ionic exchange and molecular structure on charge neutralization. This study looks into how certain cations (Na, Ca, and Mg) affect the structure of a cocamidopropyl betaine CAPB and sodium dodecylbenzenesulfonate SDBS surfactant mixture, aiming toward applications in targeted delivery systems. The mixture consists of a zwitterionic surfactant, cocamidopropyl betaine (CAPB), and an anionic surfactant, sodium dodecylbenzenesulfonate (SDBS), combined in varying molar ratios at a total concentration of 200 mM.
View Article and Find Full Text PDFPhys Rev Lett
December 2024
University of Connecticut, University of Connecticut, School of Mechanical, Aerospace, and Manufacturing Engineering, Storrs, Connecticut 06269, USA and Institute of Materials Science, Storrs, Connecticut 06269, USA.
Flat lines within a band structure represent constant frequency bands for all momentum values (i.e., they maintain zero group velocity for all wave numbers).
View Article and Find Full Text PDFPhys Rev Lett
December 2024
Brookhaven National Laboratory, Condensed Matter Physics and Materials Science Division, Upton, New York 11973, USA.
The notion of "half fire, half ice" was recently introduced to describe an exotic macroscopic ground-state degeneracy emerging in a ferrimagnet under the critical magnetic field, in which the "hot" spins are fully disordered on the sublattice with smaller magnetic moments and the "cold" spins are fully ordered on the sublattice with larger magnetic moments. Here, we further point out that this state has a twin named "half ice, half fire" in which the hot and cold spins switch positions. The new state is an excited state-thus hidden in the ground-state phase diagram-and is robust with respect to the interactions that destroy the half-fire, half-ice state.
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