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Sex and gender as predictors for allograft and patient-relevant outcomes after kidney transplantation.
Cochrane Database Syst Rev
December 2024
Sydney School of Public Health, The University of Sydney, Sydney, Australia.
Background: Sex, as a biological construct, and gender, defined as the cultural attitudes and behaviours attributed by society, may be associated with allograft loss, death, cancer, and rejection. Other factors, such as recipient age and donor sex, may modify the association between sex/gender and post-transplant outcomes.
Objectives: We sought to evaluate the prognostic effects of recipient sex and, separately, gender as independent predictors of graft loss, death, cancer, and allograft rejection following kidney or simultaneous pancreas-kidney (SPK) transplantation.
Further delineation of the SCAF4-associated neurodevelopmental disorder.
Eur J Hum Genet
December 2024
Department of Human Genetics, Inselspital Bern, University of Bern, Bern, Switzerland.
While mostly de novo truncating variants in SCAF4 were recently identified in 18 individuals with variable neurodevelopmental phenotypes, knowledge on the molecular and clinical spectrum is still limited. We assembled data on 50 novel individuals with SCAF4 variants ascertained via GeneMatcher and personal communication. With detailed evaluation of clinical data, in silico predictions and structural modeling, we further characterized the molecular and clinical spectrum of the autosomal dominant SCAF4-associated neurodevelopmental disorder.
View Article and Find Full Text PDFAssociation between ambient particulate matter and latent tuberculosis infection among 198 275 students.
J Glob Health
December 2024
Department of Chronic Communicable Disease, Center for Disease Control and Prevention of Jiangsu Province, Nanjing, China.
Background: Numerous studies have estimated the impact of outdoor particulate matter (PM) on tuberculosis risk. Nevertheless, whether there is an association between ambient PM and latent tuberculosis infection (LTBI) risk remains uncertain.
Methods: We collected the basic information and LTBI test results of students who underwent freshmen enrolment physical examinations in 68 middle schools from six prefecture-level cities located in eastern China between 2018 and 2021.
Article Synopsis
- The text discusses the importance of forecasting future health issues in the USA for effective planning and public awareness regarding disease and injury burdens.
- It describes the methodology for predicting life expectancy, cause-specific mortality, and disability-adjusted life-years (DALYs) from 2022 to 2050 using the Global Burden of Diseases framework.
- The forecasting includes various scenarios to assess the potential impacts of health risks and improvements across the country, focusing on demographic trends and health-related risk factors.
Background: Urolithiasis is a common urological problem that is associated with high morbidity. A comprehensive assessment of the non-fatal and fatal health trends of urolithiasis by age, sex, and geography over time is necessary to inform policy to control this surgically managed non-communicable disease.
Methods: This study was conducted using the standard GBD methodology and analytic tools.
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