AI Article Synopsis
- The cough reflex serves as a protective mechanism for the airway, preventing complications like bronchoaspiration.
- Chronic cough is a significant public health issue and is often the main reason for seeking medical help, functioning as a syndrome independent of its underlying causes.
- New research indicates that chronic cough involves abnormal neurophysiological processes, prompting a review of recent literature and potential therapeutic options.
Article Abstract
The cough reflex is a protective mechanism of the airway; it avoids bronchoaspiration and its complications and, when it is altered, it can appear as a hypersensitivity syndrome; cough per se is the most common symptom for which medical consultation is sought. Chronic cough represents a public health problem with a high degree of morbidity; It represents a syndrome by itself, regardless of the underlying condition. Recent evidence suggests an abnormal and altered neurophysiologic process. Recent literature and new therapeutic mechanisms were reviewed. We are in the process of understanding the cough syndrome.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.29262/ram.v66i2.565 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Effectiveness of selective NaV1.7 blocker PF-05089771 in reducing cough associated with allergic rhinitis in guinea pigs.
Respir Physiol Neurobiol
December 2024
Department of Pathophysiology Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Slovakia. Electronic address:
Background: Allergic rhinitis (AR) is a common cause of chronic cough, linked to dysregulated airway C- and Aδ-fibres through inflammatory mediators. Despite the limited efficacy of current antitussive therapies, recent studies show that the Na1.7 inhibitor can block cough in naïve guinea pigs.
View Article and Find Full Text PDFOverzealous over-the-counter cough syrup ingestion leading to serious manifestation in a child - A case report.
J Family Med Prim Care
November 2024
Department of Pediatrics, PGIMS, Rohtak, Haryana, India.
Cough is a protective reflex that allows clearance of secretions from upper respiratory tract. It is not a disease by itself but a symptom of underlying disease. In a majority of cases, it is self-limiting and requires only supportive care.
View Article and Find Full Text PDFRisk factors and outcomes of postoperative extubation failure in children with fourth ventricular tumors: a case control study.
BMC Pediatr
December 2024
Pediatric Intensive Care Unit, Guangzhou Women and Children's Medical Center (Guangzhou Medical University), Guangzhou, Guangdong, 510030, China.
Background And Objective: Microsurgical resection of tumor is an important treatment for children with fourth ventricular tumors. There is a lack of data describing risk factors for postoperative extubation failure (EF) in these children. We aimed to identify risk factors for EF in children with fourth ventricular tumors and to determine the association between EF and clinical outcomes.
View Article and Find Full Text PDFNon-pharmacological approaches to chronic cough.
J Allergy Clin Immunol Pract
December 2024
Faculty of Biology, Medicine and Health, School of Biological Sciences, Division of Infection, Immunity & Respiratory Medicine, The University of Manchester, UK; NIHR-Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, UK.
While cough is a protective reflex it can occur in the absence of any physical need to clear the airway. In chronic cough, cough can be triggered by innocuous stimuli and persist despite medical treatment. Non-pharmacological interventions such as cough control therapy, provided by speech pathologists, have gained popularity in recent years.
View Article and Find Full Text PDFTuberculosis Masquerading Foreign Body in Children.
Int J Mycobacteriol
October 2024
Faculty of Dentistry, Medical Sciences, Islamic Azad University, Tehran, Iran.
Foreign body aspiration (FBA) is a common issue in children, particularly boys, and can be life-threatening. Early removal of the foreign body (FB) leads to recovery, but delayed diagnosis may cause complications such as granuloma, recurrent pneumonia, and atelectasis. This condition often results from a child's curiosity, with factors such as inadequate swallowing reflex and activity during eating contributing to the risk.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!