We show that, for optical systems whose point spread functions exhibit isolated zeros, the information one can gain about the separation between two incoherent point light sources does not scale quadratically with the separation (which is the distinctive dependence causing Rayleigh's curse) but only linearly. Moreover, the dominant contribution to the separation information comes from regions in the vicinity of these zeros. We experimentally confirm this idea, demonstrating significant superresolution using natural or artificially created spectral doublets.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1364/OL.44.003114 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Development of oats flour and bitter gourd fortified cookies: Effects on physicochemical, antioxidant, antimicrobial, and sensory attributes.
PLoS One
January 2025
Department of Nutrition and Food Technology, Jashore University of Science and Technology, Jashore, Bangladesh.
The objective of this study was the develop of fortified cookies enriched with oats flour and bitter gourd powder and monitoring the effects of these enrichments on the physicochemical, antioxidant, antimicrobial, and sensory attributes. This study was subjected to four treatments: control (0% oats flour and bitter gourd powder), T1 (10% oats flour), T2 (3% bitter gourd powder), and T3 (7% oats flour and 3% bitter gourd powder). Various physical properties of the cookies, including weight, thickness, diameter, spread ratio, baking loss, pH, and color values (L*, a*, and b*), were measured.
View Article and Find Full Text PDFBackground: New generation PET scanners achieve superior resolution and sensitivity, but the implications on beta amyloid (Aβ) quantitation are not well understood. The Centiloid (CL) scale (Klunk et al., 2015) was introduced to promote consistent Aβ burden quantification across different positron emission tomography (PET) tracers and quantification pipelines, but was not intended to control for hardware or reconstruction changes.
View Article and Find Full Text PDFBiomarkers.
Alzheimers Dement
December 2024
Frontotemporal Disorders Unit and Massachusetts Alzheimer's Disease Research Center, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Background: Prior work has advanced our understanding of cortical atrophy in early-onset Alzheimer's disease (EOAD), but longitudinal data are sparse. Current longitudinal MRI studies point to progressive atrophy in cerebral cortex exhibiting a posterior-to-anterior gradient, but these studies include small samples with mostly amnestic EOAD. Here, we analyzed a large sample of sporadic EOAD patients from the Longitudinal Early-Onset Alzheimer's Disease Study (LEADS) to test the central hypothesis that areas in our recently described EOAD signature (Touroutoglou et al.
View Article and Find Full Text PDFBackground: The A4 Study (NCT02008357) was a multicenter, randomized, double-blind, placebo-controlled phase 3 trial, assessing the safety and efficacy of solanezumab in preclinical Alzheimer's Disease (AD). We previously reported on the baseline regional flortaucipir (FTP) profiles in this study. Here, we present the longitudinal tau profiles.
View Article and Find Full Text PDFAlzheimer's Imaging Consortium.
Alzheimers Dement
December 2024
Eli Lilly and Company, Indianapolis, IN, USA.
Background: The A4 Study (NCT02008357) was a multicenter, randomized, double-blind, placebo-controlled phase 3 trial, assessing the safety and efficacy of solanezumab in preclinical Alzheimer's Disease (AD). We previously reported on the baseline regional flortaucipir (FTP) profiles in this study1. Here, we present the longitudinal tau profiles.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!