Currently, information on the occurrence and genetic characterization of Toxoplasma gondii and Neospora caninum in tissues of rabbits in China is lacking. In this study, brain and heart samples from 470 slaughtered domestic rabbits were collected in Henan Province, Central China. The occurrence rate of T. gondii and N. caninum DNA detected by nested PCR was 2.8% and 2.1%, respectively. There were no significant differences (p > 0.05) in the frequency of the two parasite infections in relation to sex, breed, and region. Three out of 13 T. gondii-positive samples were completely or partially genotyped at 11 genetic markers using PCR-RFLP, and one was identified as ToxoDB genotype #9. For N. caninum, three different sequences at the ITS1 region and two genotypes at the MS5 microsatellite locus were identified. To our knowledge, this is the first genetic characterization of N. caninum isolates from rabbits.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6568018PMC
http://dx.doi.org/10.1051/parasite/2019035DOI Listing

Publication Analysis

Top Keywords

genetic characterization
12
occurrence genetic
8
characterization toxoplasma
8
toxoplasma gondii
8
gondii neospora
8
neospora caninum
8
slaughtered domestic
8
domestic rabbits
8
central china
8
caninum
5

Similar Publications

: Mitochondrial signatures based analysis of an emerging public health threat in India.

New Microbes New Infect

February 2025

Department of Veterinary Public Health and Epidemiology, Lala Lajpat Rai University of Veterinary and Animal Sciences, Hisar, Haryana, 125004, India.

Background: is a zoonotic tapeworm, commonly known as Asian It is an emerging sister species of with pigs as intermediate hosts. The present study aimed at genetic characterization and population structure analysis of metacestodes in slaughtered pigs in Haryana, north India.

Methods: In total, the vital organs of 253 slaughtered pigs were screened for the presence of metacestodes.

View Article and Find Full Text PDF

Background: Dysbiosis of the lung microbiome can contribute to the initiation and progression of lung cancer. Synchronous multiple primary lung cancer (sMPLC) is an increasingly recognized subtype of lung cancer characterized by high morbidity, difficulties in early detection, poor prognosis, and substantial clinical challenges. However, the relationship between sMPLC pathogenesis and changes in the lung microbiome remains unclear.

View Article and Find Full Text PDF

Background: Adenocarcinoma of the esophagogastric junction (AEGJ) is a highly aggressive tumor that frequently metastasizes to the liver. Understanding the cellular and molecular mechanisms that drive this process is essential for developing effective therapies.

Methods: We employed single-cell RNA sequencing to analyze the tumor heterogeneity and microenvironmental landscape in patients with AEGJ liver metastases.

View Article and Find Full Text PDF

Autophagic flux modulates tumor heterogeneity and lineage plasticity in SCLC.

Front Oncol

January 2025

Department of Immunology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.

Introduction: Small cell lung cancer (SCLC) is characterized by significant heterogeneity and plasticity, contributing to its aggressive progression and therapy resistance. Autophagy, a conserved cellular process, is implicated in many cancers, but its role in SCLC remains unclear.

Methods: Using a genetically engineered mouse model ( ; ; GFP-LC3-RFP-LC3△G), we tracked autophagic flux to investigate its effects on SCLC biology.

View Article and Find Full Text PDF

Assessments of genetic diversity, structure, history, and effective population size ( ) are critical for the conservation of imperiled populations. The lesser prairie-chicken () has experienced declines due to habitat loss, degradation, and fragmentation in addition to substantial population fluctuations with unknown effects on genetic diversity. Our objectives were to: (i) compare genetic diversity across three temporally discrete sampling periods (2002, 2007-2010, and 2013-2014) that are characterized by low or high population abundance; (ii) examine genetic diversity at lek and lek cluster spatial scales; (ii) identify potential bottlenecks and characterize genetic structure and relatedness; and (iii) estimate the regional .

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!