AI Article Synopsis

  • - Graft-versus-host disease (GVHD) is a serious immune response that can occur after a transplant, leading to severe health issues and potential organ failure, often resulting in death.
  • - Patients with GVHD can experience various neurological symptoms, particularly during the acute phase of the disease, which may be nonspecific.
  • - A case study of a 53-year-old woman with severe GVHD after a bone marrow transplant showed acute neurological symptoms, with MRI scans indicating conditions like Posterior Reversible Encephalopathy Syndrome and Wernicke Encephalopathy.

Article Abstract

Graft-versus-host disease (GVHD) is an immune triggered process leading to severe immune dysregulation and organ dysfunction until death and it is one of the worst medical complications after a transplant. Patients with GVHD may have several neurological alterations: during this acute severe phase there is coexistence of various and nonspecific neurological symptoms. We are reporting a case of a 53 year old woman with severe GVHD after bone marrow transplant with acute neurological signs and symptoms. MRI study showed findings consistent with Posterior reversible encephalopathy syndrome and Wernicke encephalopathy.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545363PMC
http://dx.doi.org/10.1016/j.radcr.2019.05.024DOI Listing

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