Severity: Warning
Message: fopen(/var/lib/php/sessions/ci_sessionlnj832t0g6o379eqour34esodmq01ng3): Failed to open stream: No space left on device
Filename: drivers/Session_files_driver.php
Line Number: 177
Backtrace:
File: /var/www/html/index.php
Line: 316
Function: require_once
Severity: Warning
Message: session_start(): Failed to read session data: user (path: /var/lib/php/sessions)
Filename: Session/Session.php
Line Number: 137
Backtrace:
File: /var/www/html/index.php
Line: 316
Function: require_once
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526203 | PMC |
http://dx.doi.org/10.1016/j.jare.2019.04.005 | DOI Listing |
Cancers (Basel)
December 2024
Center for Innovative Clinical Medicine, Okayama University Hospital, Okayama 700-8558, Japan.
Limited data are available on the frequency and significance of body weight loss during cancer therapy. This study investigated the frequency of patients who experienced body weight loss during immune checkpoint inhibitor (ICI) plus chemotherapy for advanced non-small cell lung cancer (NSCLC) and the impact of weight loss on treatment outcomes. Using the clinical data of 370 patients with NSCLC who received a combination of ICI and chemotherapy at 13 institutions, this study investigated the frequency of body weight loss > 5% during treatment and determined the impact of body weight loss on patient outcomes.
View Article and Find Full Text PDFPLoS One
December 2024
MS2 Discovery Interdisciplinary Research Institute, Wilfrid Laurier University, Waterloo, Canada.
Patterns in a semiarid ecosystem are important because they directly and indirectly affect ecological processes, biodiversity, and ecosystem resilience. Understanding the causes and effects of these patterns is critical for long-term land surface management and conservation efforts in semiarid regions, which are especially sensitive to climate change and human-caused disturbances. In addition, developing mathematical models is challenging because of the involvement of several interacting components within an ecosystem.
View Article and Find Full Text PDFInt J Mol Sci
November 2024
Programa de Pós-Graduação em Bioquímica e Imunologia, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, MG, Brazil.
spp. commonly infects phagocytic cells of the immune system, particularly macrophages, employing various immune evasion strategies that enable their survival by altering the intracellular environment. In mammals, these parasites establish persistent infections by modulating gene expression in macrophages, thus interfering with immune signaling and response pathways, ultimately creating a favorable environment for the parasite's survival and reproduction.
View Article and Find Full Text PDFToxins (Basel)
October 2024
Centro Bioindustrial, Instituto Butantan, São Paulo 05503-900, SP, Brazil.
This comprehensive review explores the cutting-edge advancements in snake venom research, focusing on the integration of proteomics, genomics, transcriptomics, and bioinformatics. Highlighting the transformative impact of these technologies, the review delves into the genetic and ecological factors driving venom evolution, the complex molecular composition of venoms, and the regulatory mechanisms underlying toxin production. The application of synthetic biology and multi-omics approaches, collectively known as venomics, has revolutionized the field, providing deeper insights into venom function and its therapeutic potential.
View Article and Find Full Text PDFCurr Oncol
November 2024
Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, Mexico.
Breast cancer survivorship is a recognized risk factor for sexual dysfunction, with various clinical, sociocultural, and psychological factors potentially interacting differently across populations. This study compared sexual dysfunction, anxiety, and depression between females with breast cancer and those without, aiming to identify associated factors. A total of 362 females participated, including 227 with sexual dysfunction and 135 controls.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!