Background: The construction of useful and attainable indicators of fitness assessment deserves special attention in clinical practice. We aimed to construct an indicator of the functional fitness age (FFA) of women aged 50 and older by an equation using fitness outcomes and its correlation with chronological age (CA) and to analyze the external validity of our results by comparing our sample to others.
Methods: Participants ( = 459, age: 70.3 ± 7.9 years, mean ± SD) were evaluated using the Senior Fitness Test battery. We applied a multiple regression and a subsequent Holt's exponential smoothing to analyze the outcomes.
Results: We obtained a statistically significant expression of (6, 452) = 328.384; < 0.0005 in which the coefficients of the equation explain 81% of variability ( = 0.813). The equation correlates fitness assessment in women aged 50 and over with regards to CA: FFA = 40.146 + 0.350 × CS (stand) - 0.714 × AC (rep) - 0.110 × ST (step) - 0.177 × CSR (cm) - 0.101 × BS (cm) + 8.835 × FUG (s) where CS means chair stand test, AC means arm curl test, ST means 2-min step test, CSR means chair sit-and-reach test, BS means back scratch test, FUG means 8-foot up-and-go test. We compared this index with percentiles distribution from our sample and from other studies.
Conclusion: We suggest the use of FFA as a valid indicator of fitness in adult and senior women as well as a useful motivational tool to undertake exercise programs.
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http://dx.doi.org/10.1016/j.jshs.2017.01.010 | DOI Listing |
J Cell Mol Med
January 2025
Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Induced pluripotent stem cell (iPSC)-derived natural killer (NK) cells offer an opportunity for a standardized, off-the-shelf treatment with the potential to treat a wider population of acute myeloid leukaemia (AML) patients than the current standard of care. FT538 iPSC-NKs express a high-affinity, noncleavable CD16 to maximize antibody dependent cellular cytotoxicity, a CD38 knockout to improve metabolic fitness, and an IL-15/IL-15 receptor fusion preventing the need for cytokine administration, the main source of adverse effects in NK cell-based therapies. Here, we sought to evaluate the potential of FT538 iPSC-NKs as a therapy for AML through their effect on AML cell lines and primary AML cells.
View Article and Find Full Text PDFSensors (Basel)
January 2025
School of Integrated Health Sciences, Department of Kinesiology and Nutrition Sciences, University of Nevada, Las Vegas, NV 89154, USA.
Introduction: As wearable technology becomes increasingly popular and sophisticated, independent validation is needed to determine its accuracy and potential applications. Therefore, the purpose of this study was to evaluate the accuracy (validity) of VO2max estimates and blood oxygen saturation measured via pulse oximetry using the Garmin fēnix 6 with a general population participant pool.
Methods: We recruited apparently healthy individuals (both active and sedentary) for VO2max (n = 19) and pulse oximetry testing (n = 22).
Nutrients
January 2025
Faculty of Health, Santo Tomas University, Talca 3460000, Chile.
Cardiovascular diseases increasingly impact youth, with early development of risk factors such as obesity, hypertension, and inadequate nutrient intake. Proper nutrient intake and physical fitness are vital for reducing these risks, especially in pediatric populations. This study explores the connection between physical fitness, metabolic risk, and nutrient status among 1656 Chilean schoolchildren from diverse socio-economic backgrounds.
View Article and Find Full Text PDFNutrients
December 2024
Rehabilitation Research Centre (REVAL), Rehabilitation Sciences and Physiotherapy, Hasselt University, Wetenschapspark 7, 3590 Diepenbeek, Belgium.
Background: Malnutrition has extensive consequences, affecting multiple levels of functioning, including motor skill impairments. However, current interventions have mainly focused on dietary treatment, often neglecting motor impairments and relying solely on clinical and anthropometric indicators to assess treatment response. This study aims to bridge this gap by examining the combined effect of ready-to-use supplementary food (RUSF) and high-intensity motor learning (HiML) on motor skill-related physical fitness in children with moderate thinness (MT).
View Article and Find Full Text PDFInt J Mol Sci
December 2024
Department of Diabetes and Endocrine Medicine, Graduate School of Medicine and Dental Sciences, Kagoshima University, Kagoshima 890-8544, Japan.
Omega-3 (ω-3) polyunsaturated fatty acids in fish oil have been shown to prevent diet-induced obesity in lean mice and to promote heat production in adipose tissue. However, the effects of fish oil on obese animals remain unclear. This study investigated the effects of fish oil in obese mice.
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