An acid hydrolysis ultrahigh-performance LC-UV method was evaluated for the determination of total amino acids in infant formula and adult/pediatric nutritional formula. It was assessed for compliance against AOAC INTERNATIONAL (SMPR) established by the Stakeholder Panel for Infant Formula and Adult Nutritionals (SPIFAN). A single-laboratory validation (SLV) study was conducted as a first step in the process to validate the method. In this SLV, 17 SPIFAN matrices representing a range of infant formula and adult nutritional products were evaluated for their amino acid content. The analytical range was found to be within the needs for all products; some may require a dilution. Evaluation of trueness performed on Standard Reference Material 1849a (Infant/Adult Nutritional Formula) showed all compounds met the SMPR theoretical value, with exceptions for threonine and tyrosine. These may have a bias for the National Institute of Standards and Technology (NIST) data, depending on hydrolysis used in the determination of the NIST certificate of analysis. Based on the results of this SLV, this method met the SMPR and was approved as a First Action method by the AOAC Expert Review Panel on Nutrient Methods on August 28, 2018.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.5740/jaoacint.19-0036 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Comparison of fluoride level between mother's milk and infant formula milk - a global systematic review and dental fluorosis risk assessment.
Food Addit Contam Part A Chem Anal Control Expo Risk Assess
January 2025
Department of Pediatrics and Neonatology, Guangzhou University of Traditional Chinese Medicine Dongguan Hospital, Guangdong Province, China.
Dental Fluorosis (DF) is one of the negative outcomes of excessive fluoride (F) intake through food sources. This systematic review aimed to compare F content in two important food sources for infants, Mother's Milk (MoM) and Infant Formula (IF), and then evaluate the risk of DF related to F in those two types of food. For this purpose, 181 studies were initially found by searching the relevant keywords in widely recognized databases, including Google Scholar, Scopus, Science Direct, and PubMed.
View Article and Find Full Text PDFAn Overview of Early-Life Gut Microbiota Modulation Strategies.
Ann Nutr Metab
January 2025
Department of Paediatrics, Medical University of Warsaw, Warsaw, Poland.
Background: The gut microbiota, or microbiome, is essential for human health. Early-life factors such as delivery mode, diet, and antibiotic use shape its composition, impacting both short- and long-term health outcomes. Dysbiosis, or alterations in the gut microbiota, is linked to conditions such as allergies, asthma, obesity, diabetes, inflammatory bowel disease, and necrotizing enterocolitis in preterm infants.
View Article and Find Full Text PDFDevelopment and Validation of a Decision Support Tool for Baby Formula Prescription.
Matern Child Health J
January 2025
Postgraduate Program in Collective Health, Faculty of Health Sciences of Trairi, Federal University of Rio Grande do Norte, Santa Cruz, Brazil.
Introduction: Although there are acceptable medical reasons for the use of food supplements, most prescriptions for newborns do not comply with current recommendations, putting continued breastfeeding at risk. This study aimed to create and validate a flowchart for newborn supplement prescription.
Methods: The flowchart was created and submitted to two rounds of assessments by a panel of judges, who calculated the content validity index (CVI) (acceptable > 0.
Does Mother's Nutritional Knowledge Level Affect Anthropometric Measurements of 0-2 Year Old Infants?
Ecol Food Nutr
January 2025
Department of Nutrition and Dietetics, Faculty of Health Sciences, Eastern Mediterranean University, Famagusta, Turkey.
The objective of this study was to investigate the relationship between maternal nutritional knowledge and anthropometric indices in children under 2 years of age. The Infant Nutrition Attitude Scale (IOWA) was administered to all participated mothers. The IOWA was developed to assess women's attitudes toward breastfeeding and their choice of infant feeding method.
View Article and Find Full Text PDFFollowing a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on the safety of an oil derived from the microalga sp. (strain ATCC-20889) as a novel food (NF) pursuant to Regulation (EU) 2015/2283. The NF is a mixture of triglycerides in which docosahexaenoic acid (DHA) represents 40%-43% of fatty acids.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!