Clinicians seek to pursue the most clinically effective treatment strategies, but costs have also become a key determinant in contemporary health care. Economic analyses have thus emerged as a valuable resource to both quantify and qualify the value of existing and emerging interventions and programs. Cost-effectiveness analyses estimate the benefits gained per monetary unit, providing insights to guide resource allocation. Herein, we delineate the related concepts and considerations to facilitate understanding and appraisal of these analyses, so as to better inform the stakeholders in our otolaryngology community.
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http://dx.doi.org/10.1177/0194599819852104 | DOI Listing |
J Biomed Mater Res B Appl Biomater
February 2025
Bioassays and Cellular Dynamics Lab, Department of Chemical and Biological Sciences, Institute of Biosciences, UNESP: São Paulo State University, São Paulo, Brazil.
Calcium phosphates, notably monetite, are valued biomaterials for bone applications owing to their osteogenic properties and rapid uptake by bone cells. This study investigates the enhancement of these properties through Cobalt doping, which is known to induce hypoxia and promote bone cell differentiation. Heat treatments at 700°C, 900°C, and 1050°C are applied to both monetite and Cobalt-doped monetite, facilitating the development of purer, more crystalline phases with varied particle sizes and optimized cellular responses.
View Article and Find Full Text PDFVaccines (Basel)
January 2025
Pfizer Ltd., Tadworth KT20 7NY, UK.
Background/objectives: Respiratory syncytial virus (RSV) is a leading cause of respiratory infections in children. A novel RSVpreF vaccine for use among pregnant women for the prevention of RSV in infants is expected to be licensed in Mexico. Hence, the clinical and economic burden of RSV among infants in Mexico, with and without a year-round RSVpreF maternal vaccination program, was estimated.
View Article and Find Full Text PDFJ Music Ther
January 2025
Department of Communication and Psychology, Aalborg University, 9220, Denmark.
The cost-effectiveness of an intervention is an important factor in health care decisions about which health care services should be publicly funded and/or approved as an eligible intervention for private insurance coverage. Music therapy as a health profession lacks substantial research on the cost-effectiveness of its services and there is no overview of existing data. We therefore conducted a scoping review.
View Article and Find Full Text PDFAm J Lifestyle Med
January 2025
Massachusetts College of Pharmacy and Health Sciences, School of Pharmacy, Department of Pharmaceutical and Administrative Sciences, Boston, MA, USA.
Based on previously published US Diabetes Prevention Program (DPP) cost-effectiveness analyses (CEAs), metformin continues to be promoted as "cost-effective." We reviewed a 10-year CEA to assess this. Treatment alternatives included placebo, branded metformin and individual lifestyle modification.
View Article and Find Full Text PDFDiabetologia
January 2025
MRC Epidemiology Unit, School of Clinical Medicine, University of Cambridge, Cambridge, UK.
Aims/hypothesis: UK standard care for type 2 diabetes is structured diabetes education, with no effects on HbA, small, short-term effects on weight and low uptake. We evaluated whether remotely delivered tailored diabetes education combined with commercial behavioural weight management is cost-effective compared with current standard care in helping people with type 2 diabetes to lower their blood glucose, lose weight, achieve remission and improve cardiovascular risk factors.
Methods: We conducted a pragmatic, randomised, parallel two-group trial.
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