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Compassionate Use of Letermovir in a 2-Year-Old Immunocompromised Child With Resistant Cytomegalovirus Disease. | LitMetric
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Compassionate Use of Letermovir in a 2-Year-Old Immunocompromised Child With Resistant Cytomegalovirus Disease.

Maria Pérez Marín Laurent Arthur Decosterd Pascal Andre Thierry Buclin Thomas Mercier Kristina Murray Mattia Rizzi Pascal Meylan Katia Jaton-Ogay Onya Opota Carole Gengler Marie-Hélène Perez Julia Natterer Sandra Andrea Asner

J Pediatric Infect Dis Soc

Pediatric Infectious Diseases and Vaccinology Unit, Woman-Mother-Child Department, University Hospital Center and University of Lausanne, Switzerland.

Published: February 2020

Little information on the efficacy and pharmacokinetics of letermovir among immunocompromised children is currently available. We describe here the use of letermovir in a 2-year-old immunocompromised child with ganciclovir-resistant cytomegalovirus disease who required extracorporeal membrane oxygenation. Detailed information on therapeutic-drug-monitoring measures and dosage adjustments for letermovir is provided.

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 Source
http://dx.doi.org/10.1093/jpids/piz033DOI Listing

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