Introduction: The routinely use of drains in thyroid surgery is a traditional and well-defined method, even if there is no clear evidence of significant improvement in patients outcomes. Aim of our study is to define the feasibility, safety and cost- effectiveness of fibrin sealant in total thyroidectomy in order to overcome the use of drains.
Materials And Methods: We enrolled 262 patients (45 men and 217 women, mean age 54.7 yrs) undergone total thyroidectomy in University Hospital of Palermo (Italy), between July 2015 and October 2017. We randomized patients into group A (drain) and group B (no drain, fibrin sealant application).
Results: We registered statistical difference between the two groups in mean operative time, visual analogue scale of pain, post-operative stay, incidence of seromas and/or deep and superficial hematomas, re-operation and wound infection (reduced in the fibrin sealant group). No significant difference have been found in intraoperative blood loss, postoperative cough, post-operative use of analgesic and in incidence of hypoparathyroidism or recurrent palsy.
Conclusions: Our study demonstrates that there is no evidence that the use of suction drains improves patients outcome and that routinely use of fibrin sealant can be advocated in thyroid surgery as an adjunct to a good surgical procedure.
Key Words: Complication, Drainage, Fibrin Sealant, Thyroidectomy.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Could Fibrin Sealants (TISSEEL) Be Effective in the Management of Burn Injuries? A Histopathological Study in Rats.
Med Sci (Basel)
December 2024
Laboratory of Experimental Surgery and Surgical Research "N.S. Christeas", School of Medicine, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Burn injuries remain a major clinical problem worldwide, which require special management by experienced plastic surgeons. However, they cannot be available in every healthcare unit; consequently, there is a need for effective treatment options that could be utilized by a wide range of non-expert healthcare professionals. The aim of the present experimental study was to investigate the safety and efficacy of using a fibrin sealant (TISSEEL) compared to the conventional treatment with sulfadiazine on partial-thickness burn in a rat animal model.
View Article and Find Full Text PDFEfficacy of Fibrin Sealant in Submental Liposuction: A Prospective Randomized Study.
Aesthetic Plast Surg
December 2024
Tokyo Chuo Beauty Clinic, K's Square Building 3F, 2-8-15 Sonezaki, Kita-ku, Osaka-shi, Osaka-fu, UmedaOsaka, Japan.
Background: The incidence rate of submental liposuction has been increasing in recent years. Although this procedure is relatively simple, serious complications, including fatalities, have been reported, primarily owing to intraoperative and postoperative bleeding.
Methods: To enhance the safety of liposuction, we examined the efficacy of Beriplast® P (CSL Behring, Melbourne, Australia), a physiological tissue adhesive fibrin sealant, in reducing postoperative swelling.
Background And Aims: An effective surgical adhesive must possess strength, biodegradability, flexibility, non-toxicity, and the ability to accommodate to tissue movement. However, existing adhesives in the market lack some of these crucial properties. Both synthetic cyanoacrylate and natural fibrin glue have been explored for sutureless oral surgery, but they come with specific limitations.
View Article and Find Full Text PDFLong-term Investigation of Annulargrams and Intra-annular Fibrin to Treat Chronic Discogenic Low Back Pain and Radiculopathy: 1-, 2-, and 3-Year Outcome Comparisons of Patients with and without Prior Surgery.
Pain Physician
November 2024
Longevity-New York, New York City, New York, USA; Institute for Mobility and Longevity, Ft. Myers, FL, USA; 411th Hospital Center, Armed Forces Reserve Center, Jacksonville, FL, USA; Adam Vital Hospital, Dubai, Unted Arab Emirates; Reem Hospital, Abu Dhabi, United Arab Emirates.
Article Synopsis
- Discogenic chronic low back pain (cLBP) and radiculopathy are common and disabling, with traditional treatments often leading to further complications or degeneration of spinal discs.
- A new treatment strategy focuses on diagnosing and treating annulus fibrosus tears by using fibrin to seal these injuries and promote tissue growth, potentially offering a safer and more effective alternative.
- This method was tested in a retrospective cohort study involving patients who had not found relief from multiple prior treatments for cLBP lasting over six months, utilizing MRI for diagnosis.
Fibrin-glue-assisted retinopexy for coloboma-associated retinal detachment.
Indian J Ophthalmol
December 2024
Srimati Kanuri Santhamma Center for Vitreo-Retinal Diseases, Anant Bajaj Retina Institute, L. V. Prasad Eye Institute, Hyderabad, Telangana, India.
Background: Retinal detachment (RD) is common (23%-40%) in eyes with uveal coloboma due to early vitreous syneresis, inherent defects at the locus minoris resistentiae, and breaks in intercalary membrane (ICM).[1] Managing eyes with coloboma RD is difficult due to complexity of accessing and repairing retinal breaks. In RD surgeries, tamponade agents are used to provide surface tension across retinal breaks to prevent further fluid flow into the subretinal space until the effect of retinopexy is permanent.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!