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| http://dx.doi.org/10.21037/jtd.2019.02.98 | DOI Listing |
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New approaches to secondary metabolite discovery from anaerobic gut microbes.
Appl Microbiol Biotechnol
January 2025
Department of Chemical Engineering, University of California, Santa Barbara, CA, 93106, USA.
The animal gut microbiome is a complex system of diverse, predominantly anaerobic microbiota with secondary metabolite potential. These metabolites likely play roles in shaping microbial community membership and influencing animal host health. As such, novel secondary metabolites from gut microbes hold significant biotechnological and therapeutic interest.
View Article and Find Full Text PDFPerformance-based and patient-reported outcome measures for custom ankle-foot orthosis users: reliability, validity, and sensitivity evidence.
Disabil Rehabil
January 2025
Shirley Ryan AbilityLab, Chicago, IL, USA.
Purpose: To evaluate the psychometric properties of performance and patient-reported outcome measures (PROMs) for custom ankle-foot orthosis (AFOs) users.
Materials And Methods: Current AFO users completed two assessments one week apart; new AFO users completed an assessment before device delivery and at one- and two-months post-delivery.
Results: Seventy current and 31 new users consented and provided data.
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Cureus
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Otolaryngology-Head and Neck Surgery, College of Medicine, King Saud University, Riyadh, SAU.
The rapid evolution of generative artificial intelligence (AI) has introduced transformative technologies across various domains, with text-to-video (T2V) generation models emerging as transformative innovations in the field. This narrative review explores the potential of T2V AI generation models used in healthcare, focusing on their applications, challenges, and future directions. Advanced T2V platforms, such as Sora Turbo (OpenAI, Inc.
View Article and Find Full Text PDFQuince Powder Increases Antioxidant Activity and Probiotic Survival in Yoghurt.
Food Technol Biotechnol
December 2024
Department of Dairy Technology, Faculty of Agriculture, Ege University, Bornova, Izmir, Turkey.
Research Background: In recent years, there has been a growing interest in incorporating fruit-based additives into yogurt formulations as a means to improve the functionality of the product. This study aims to produce a functional product by incorporating quince, which is rich in fibre, vitamins, minerals and antioxidant activity, into a yoghurt formulation.
Experimental Approach: The influence of the addition of quince powder (0 (control), 0.
Training T-shaped translational scientists.
J Clin Transl Sci
December 2024
Center for Clinical and Translational Science, University of Alabama at Birmingham, Birmingham, AL, USA.
Unlabelled: To evaluate the design of I-Corps@NCATS as a translational scientist training program, we mapped specific elements of the program's content and pedagogy to the characteristics of a translational scientist, as first defined by Gilliland et al. []: systems thinker, process innovator, boundary spanner, team player, and skilled communicator. Using a mixed-methods evaluation, we examined how the I-Corps@NCATS training program, delivered across twenty-two Clinical and Translational Science Award Hubs, impacted the development of these key translational scientist characteristics.
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