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[Dissolution and maintenance of portal vein thrombosis with antithrombin III and edoxaban in liver cirrhosis:a case report]. | LitMetric

AI Article Synopsis

  • * He received an Antithrombin III (ATIII) formulation, which effectively lysed the thrombus within 2 days, followed by edoxaban to prevent future clots.
  • * After 4 months of maintenance therapy with edoxaban, the patient showed no signs of recurrent portal vein thrombosis, suggesting that this combination therapy could be a viable treatment option.

Article Abstract

A male patient in his 70s was referred to our department. He was found to have alcoholic liver cirrhosis, esophageal varices, and portal vein thrombosis. Antithrombin III (ATIII) formulation was administered. The thrombus was almost completely lysed 2 days after administration. Because portal vein thrombosis could recur, edoxaban, a direct oral anticoagulant (DOAC), was introduced to prevent recurrence. After 4 months, he showed no recurrence of portal vein thrombosis. In the present case, the combination of an ATIII formulation as initial treatment and edoxaban as maintenance therapy was safe and effective. The combination of ATIII and edoxaban may be a treatment option for patients with portal vein thrombosis.

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Source
http://dx.doi.org/10.11405/nisshoshi.116.523DOI Listing

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