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[Pathology and Acute Phase Treatment of Osteoporotic Vertebral Fractures:Indications and Techniques for Vertebroplasty].
No Shinkei Geka
January 2025
Department of Neurosurgery, Takeda General Hospital.
Vertebroplasty has shown excellent analgesic effects in patients with osteoporotic vertebral fractures. In Japan, percutaneous vertebroplasty, balloon kyphoplasty, and vertebral body stenting are commonly performed. All of these techniques require precise transpedicular vertebral puncture and complete cement filling without leakage.
View Article and Find Full Text PDFState-of-the-art progress and prospect of metal-organic frameworks and composites for photoelectrochemical amino-drugs sensing.
Environ Res
January 2025
Energy Convergence Research Center, Seoul National University of Science and Technology, 232 Gongneung-ro, Nowon-gu, Seoul, 01811, Republic of Korea; Department of Fine Chemistry, Seoul National University of Science and Technology, 232, Gongneung-ro, Nowon-gu, Seoul 01811, Republic of Korea; Institute for Applied Chemistry, Seoul National University of Science and Technology, 232 Gongneung-ro, Nowon-gu, Seoul 01811, Republic of Korea. Electronic address:
Unregulated discharge of antibiotics in waterbodies has posed significant threat to the aquatic flora and fauna in post-pandemic times. This alarming situation has ascertained the need for suitable sensors to detect persistent antibiotic residues. In this context, functional hybrid materials centralized on reticular metal-organic frameworks (MOFs)/composites have been a research hot spot for photoelectrochemical host-guest recognition events over the past two decades.
View Article and Find Full Text PDFEHM: Exploring dynamic alignment and hierarchical clustering in unsupervised domain adaptation via high-order moment-guided contrastive learning.
Neural Netw
January 2025
College of Information Science & Electronic Engineering, Zhejiang University, Hangzhou, 310027, China. Electronic address:
Unsupervised domain adaptation (UDA) aims to annotate unlabeled target domain samples using transferable knowledge learned from the labeled source domain. Optimal transport (OT) is a widely adopted probability metric in transfer learning for quantifying domain discrepancy. However, many existing OT-based UDA methods usually employ an entropic regularization term to solve the OT optimization problem, inevitably resulting in a biased estimation of domain discrepancy.
View Article and Find Full Text PDFMultiplex generation and single-cell analysis of structural variants in mammalian genomes.
Science
January 2025
Department of Genome Sciences, University of Washington, Seattle, WA, USA.
Studying the functional consequences of structural variants (SVs) in mammalian genomes is challenging because (i) SVs arise much less commonly than single-nucleotide variants or small indels and (ii) methods to generate, map, and characterize SVs in model systems are underdeveloped. To address these challenges, we developed Genome-Shuffle-seq, a method that enables the multiplex generation and mapping of thousands of SVs (deletions, inversions, translocations, and extrachromosomal circles) throughout mammalian genomes. We also demonstrate the co-capture of SV identity with single-cell transcriptomes, facilitating the measurement of SV impact on gene expression.
View Article and Find Full Text PDFUnveiling hotspots of emerging research in the miRNA-related mechanism underlying cancer through comprehensive bibliometric analysis with implications for precision medicine and non-invasive diagnostics.
Front Oncol
January 2025
Department of Colorectal Hernia Surgery, Binzhou Medical University Hospital, Binzhou, Shandong, China.
Background And Objective: MicroRNAs (miRNAs) are implicated in cancer by exerting roles in tumor growth, metastasis, and even drug resistance. The general trends of miRNA research in diverse cancers are not fully understood. In this work, miRNA-related research in colorectal cancer, prostate cancer, leukemia, and brain tumors was analyzed in search of key research trends with clinical potential.
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