This simultaneous replication single-case design study investigated a vocabulary and main idea intervention with an aspect of text choice provided to students with autism spectrum disorder (ASD). Five middle school students with ASD participated in two instructional groups taught by school-based personnel. Results were initially mixed. These results were followed by upward and stable trends, indicating a functional relationship between the independent and dependent variables. Social validity measures indicated that students appreciated the opportunity to make choices on text selection.
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http://dx.doi.org/10.1177/0145445519853781 | DOI Listing |
J Immunotoxicol
October 2024
Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Belvaux, Luxembourg.
This work focuses on the need for modeling and predicting adverse outcomes in immunotoxicology to improve nonclinical assessments of the safety of immunomodulatory therapies. The integrated approach includes, first, the adverse outcome pathway concept established in the toxicology field, and, second, the systems medicine disease map approach for describing molecular mechanisms involved in a particular pathology. The proposed systems immunotoxicology workflow is illustrated with chimeric antigen receptor (CAR) T cell treatment as a use case.
View Article and Find Full Text PDFPeerJ Comput Sci
October 2024
Department of Visual Communication Design, Tongmyong University, Busan, Republic of South Korea.
The evolution of a city is significantly shaped by the design of its urban landscape. The advancement of artificial intelligence has substantially increased convenience for individuals. This research proposes an urban landscape layout model powered by artificial intelligence that automatically generates urban landscape design based on deep learning (URDDL) with two dimensions: emotional tendency and urban landscape appraisal.
View Article and Find Full Text PDFJ Int Neuropsychol Soc
December 2024
Department of Neurology, Emory University School of Medicine, Atlanta, GA, USA.
Objective: To evaluate the impact of receptive vocabulary versus years of education on neuropsychological performance of Black and White older adults.
Method: A community-based prospectively enrolled cohort ( = 1,007; 130 Black, 877 White) in the Emory Healthy Brain Study were administered the NIH Toolbox Picture Vocabulary Test and neuropsychological measures. Group differences were evaluated with age, sex, and education or age, sex, and Toolbox Vocabulary scores as covariates to determine whether performance differences between Black versus White participants were attenuated or eliminated.
J Sex Med
November 2024
Discipline of Obstetrics and Gynecology, Faculty of Medicine, Memorial University, St. John's, NL, A1B 3V6, Canada.
Introduction: Localized provoked vulvodynia is a common sexual health condition for which there is a lack of consensus on effective management, even though it can have a significant negative impact on psychological wellbeing, sexual functioning, and quality of life for women and their partners.
Aim: To map the research landscape related to the effectiveness/efficacy of psychological treatments for localized provoked vulvodynia, identify gaps, and make recommendations for future research.
Methods: We used Arksey and O'Malley's approach to conducting a scoping review to identify, organize, and summarize research published between 2010 and 2023 that investigated the efficacy or effectiveness of interventions in the management of localized provoked vulvodynia.
JAMA Neurol
November 2024
University of Pittsburgh, Pittsburgh, Pennsylvania.
Importance: Antiseizure medications (ASMs) are potential teratogens commonly prescribed for multiple indications. ASM fetal exposure can impair neurodevelopment. Folate improves pregnancy outcomes, but higher doses may pose risks.
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