Department of Transplantation, Instituto Nacional de Ciencias Médicas y Nutrición "Salvador Zubirán" (INCMNSZ), Mexico City, Mexico.
Published: September 2020
AI Article Synopsis
Article Abstract
We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 95 Mexicans from the state of Aguascalientes to obtain information regarding allelic and haplotypic frequencies and their linkage disequilibrium. We find that the most frequent haplotypes in the state of Aguascalientes include four Native American, three European and one Asian haplotypes. Admixture estimates revealed that the main genetic components in the state of Aguascalientes are Native American (54.53 ± 3.22% by ML; 44.21% of Native American haplotypes) and European (44.34 ± 0.45% by ML; 40.53% of European haplotypes), and a relatively low African genetic component (1.13 ± 2.33% by ML; 5.26% of African haplotypes).
Laboratorio de Biología Celular y Tisular, Departamento de Morfología, Centro de Ciencias Básicas, Universidad Autónoma de Aguascalientes, Aguascalientes 20100, Mexico.
is a leading cause of healthcare-associated infections, which are related to substantial morbidity and mortality. The incidence of Plasmid-Mediated Quinolone Resistance (PMQR) determinants has been previously reported in this bacterium. However, there is limited information regarding the presence of PMQR and carbapenemase-encoding genes simultaneously.
The World Health Organization emphasizes that health involves complete well-being, not just the absence of illness, highlighting the importance of mental health beyond mere lack of disorders.
In Mexico, the prevalence of mental and behavioral disorders (MBD) was found to be 9.3%, with anxiety and obsessive-compulsive disorder being the most common at 39.8%.
Identifying these prevalence rates is crucial for healthcare professionals to enhance the quality of care and follow-up for patients affiliated with the Mexican Institute for Social Security (IMSS).
Several external and internal factors can affect the performance and variability of Hemoglobin concentration [Hb] measurements using HemoCue, and documentation on the contribution of different sources of [Hb] variation is limited. We used an experimental repeated measurements design with nine randomly selected participants, three HemoCue devices, and three trained field workers. HemoCue measurements for all samples were repeated three times.
Purpose: Immunoglobulin replacement therapy remains a cornerstone of treatment in antibody deficiencies and other inborn errors of immunity. While patient preferences between subcutaneous and intravenous immunoglobulin have been studied through questionnaires, no study has yet explored patient perspectives in a free environment. Therefore, we aimed to conduct a sentiment analysis as well as a temporal and geographical analysis on public opinions obtained from social media to better understand patient satisfaction and public perception on immunoglobulin therapy.
Aguascalientes has a high rate of kidney failure in young adults, potentially linked to low kidney volume (KV) at birth and exposure to harmful substances (xenobiotics).
The study involved 299 healthy pregnant women, analyzing their urine, amniotic fluid, and their newborns' urine to measure various toxic metals and pesticides, alongside calculating the total kidney volume.
Results indicated that exposure to specific pesticides and fluoride during pregnancy correlated with low kidney volume in infants, suggesting a possible connection to kidney health issues and electrolyte imbalances.
