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Investigating the key principles in two-step heterogeneous transfer learning for early laryngeal cancer identification.
Sci Rep
January 2025
Faculty of Applied Sciences, Macao Polytechnic University, Macao, 999078, China.
Data scarcity in medical images makes transfer learning a common approach in computer-aided diagnosis. Some disease classification tasks can rely on large homogeneous public datasets to train the transferred model, while others cannot, i.e.
View Article and Find Full Text PDFGenetically predicted immune cells mediate the association between gut microbiota and autoimmune liver diseases.
Front Microbiol
December 2024
General Surgery Department, Nanjing Pukou District Traditional Chinese Medicine Hospital, Nanjing, China.
Article Synopsis
- Researchers examined the link between gut microbiota and Autoimmune Liver Diseases (AILDs) using Mendelian Randomization, a method to infer causal relationships while minimizing bias.
- Their analysis found that a higher involvement of gut microbiota correlates with increased risk for Autoimmune Hepatitis (AIH) and Primary Sclerosing Cholangitis (PSC), with immune cells mediating part of this risk.
- The study indicates that understanding these immune mechanisms could help inform preventive strategies for managing AILDs in clinical settings.
Percutaneous Transhepatic Cholangioscopy in Hepatolithiasis Associated With Decompensated Cirrhosis: A Retrospective Cohort Study.
J Evid Based Med
December 2024
Research Center of Biliary Disease, West China Hospital, Sichuan University, Chengdu, China.
Background: Multiple and complicated hepatolithiasis can be associated with decompensated cirrhosis. Endoscopic retrograde cholangiopancreatography is unavailable for multiple and complicated hepatolithiasis, and the mainstay for decompensated cirrhosis is liver transplantation. However, due to the ethical factors and the complexity of operation, liver transplantation cannot be widely operated.
View Article and Find Full Text PDFInvestigating precise control pathway for haemostatic clip usage in laparoscopic cholecystectomy based on patient clinical variations: an exploratory retrospective observational study.
BMJ Open
August 2024
Department of Equipment and Materials, West China Hospital of Sichuan University, Chengdu, Sichuan, China
Article Synopsis
- The study aimed to establish a control pathway for using haemostatic clips in laparoscopic cholecystectomy (LC) based on patient clinical variations to optimize consumption and reduce costs.
- Researchers conducted a retrospective observational study using data from 1001 patients who underwent LC, identifying key factors influencing clip usage.
- The findings showed that conditions like acute cholecystitis and anatomical variations significantly impacted clip use, with recommendations suggesting a maximum of three clips in about 17.3% of cases for better resource management.
Does Colonoscopy as a First Screening Test Still Make Sense?-Counterpoint.
Dig Dis Sci
December 2024
Department of Internal Medicine, National Taiwan University Hospital, No. 7, Chung-Shan South Road, Taipei, Taiwan.
Colonoscopy has been widely regarded as the gold standard for its high diagnostic accuracy and preventive potential. However, its invasive nature, high cost, and suboptimal participation rates limit its utility at the population level. Non-invasive screening tests, notably the fecal immunochemical test (FIT) and multitarget stool DNA tests, present promising alternatives that may improve screening participation and reduce barriers to participation.
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