Context.—: The Kleihauer-Betke (KB) test is validated for estimating the dose of Rh immune globulin needed for Rh-negative pregnant females. However, some clinicians are also ordering the test for Rh-positive women. The degree to which this practice occurs is unknown.
Objective.—: To evaluate the number of laboratories that perform the KB test on Rh-positive pregnant women, and to establish current ordering practices for this indication.
Design.—: We added 9 supplemental questions regarding KB test use for fetomaternal hemorrhage to the 2016 College of American Pathologists proficiency test survey. We also reviewed the available literature regarding the diagnostic utility of the KB test for Rh-positive women.
Results.—: A total of 1578 surveys were evaluated and revealed that 52% (824) of respondents perform these tests for Rh-positive women, and more than 50% (440 of 819; 53.7%) of these laboratories report that the results for Rh-positive women are treated as important or very important.
Conclusions.—: The KB test is commonly used for Rh-positive women, and the information obtained from the test is considered as urgent and important. However, the available literature in support of this practice is still nonconclusive.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.5858/arpa.2018-0523-CP | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Analysis of pregnancy and neonatal outcomes in 100 pregnant women with Rh-negative blood type.
BMC Pregnancy Childbirth
December 2024
Department of Obstetrics, The Second Affiliated Hospital of Guangxi Medical University, Nanning, 530007, Guangxi, China.
Background: This study aimed to explore variations in prenatal care, delivery methods, influencing factors, and neonatal outcomes among Rh-negative pregnant women, so as to improve pregnancy healthcare for this demographic, raise the quality of maternal-fetal management, and safeguard the health of both mother and infant.
Methods: This study included 200 women who received routine prenatal care, exhibited no other pregnancy complications, and were admitted for delivery. They were divided into an observation group (100 Rh-negative blood type) and a control group (100 Rh-positive blood type).
Colombian consensus for the diagnosis, prevention, and management of Rhesus disease.
Rev Colomb Obstet Ginecol
September 2024
Unidad de Medicina Materno Fetal, Clínica Del Prado, Universidad CES. Medellín (Colombia); Fundared Materna. Bogotá (Colombia).
Article Synopsis
- Aiming to standardize care for Rh-D negative pregnant women, a panel of 23 experts developed guidelines focused on prevention and management of Rh isoimmunization and related conditions to improve perinatal outcomes.* -
- Utilizing a modified Delphi method, the panel assessed 22 questions across eight key areas, including Rh-D testing, prenatal care, and treatment strategies for affected fetuses, reaching an 80% consensus on recommendations.* -
- Key recommendations include encouraging preconception consultations for Rh-D negative women, determining maternal Rh-D status during initial healthcare visits, and ascertaining the father's Rh-D status early in prenatal care.*
Prevalence and Associated Factors of Jaundice Among Neonates Admitted to Neonatal Intensive Care Units at Public Specialized Hospitals in Bahir Dar City, Northwest Ethiopia.
Glob Pediatr Health
October 2024
Department of Pediatrics and Child Health Nursing, School of Nursing, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Article Synopsis
- Neonatal jaundice is more prevalent and complex in low and middle-income countries, with limited data on its prevalence in Ethiopia.
- A study conducted in Bahir Dar city found that 38.8% of the 340 neonates admitted to the neonatal intensive care unit had jaundice.
- Key factors contributing to neonatal jaundice included being male, prematurity, maternal blood type (especially Rh negative or AB), and ABO incompatibility, indicating a need for improved antenatal blood testing and accessible treatment options.
Assessment of erythrocyte alloimmunization among patients treated at a Brazilian university hospital.
Hematol Transfus Cell Ther
November 2024
Instituto de Ciências Biomédicas (ICBIM), Universidade Federal de Uberlândia (UFU), Uberlândia, MG, Brazil. Electronic address:
Article Synopsis
- This study investigates the frequency of alloimmunization among patients at a Brazilian university hospital, focusing on demographic and clinical characteristics of those with positive irregular antibody screenings.
- Findings reveal that women were more likely to be alloimmunized, with common blood groups A and O, and anti-D, anti-E, and anti-Kell antibodies frequently detected.
- The research emphasizes the importance of thorough antibody screening and erythrocyte immunophenotyping to enhance the safety and effectiveness of blood transfusions in clinical settings.
Prevalence of unexpected red blood cell antibodies in pregnant women and follow-up of pregnancy outcome in pregnant women treated with intra-uterine transfusion.
Asian J Transfus Sci
February 2024
Department of Transfusion Medicine, Medanta - The Medicity, Gurugram, Haryana, India.
Background: For the management of hemolytic disease of the fetus and newborn (HDFN), it is important to detect unexpected red cell antibody in pregnant women. We assessed the prevalence of unexpected red cell antibodies in consecutive pregnant women attending antenatal clinic (ANC). More importantly, cases with unexpected antibody causing severe anemia were followed-up for intervention (Intra-uterine transfusion {IUT}) and outcome of pregnancy (still-birth/live-healthy).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!