The one-inflated positive Poisson mixture model (OIPPMM) is presented, for use as the truncated count model in Horvitz-Thompson estimation of an unknown population size. The OIPPMM offers a way to address two important features of some capture-recapture data: one-inflation and unobserved heterogeneity. The OIPPMM provides markedly different results than some other popular estimators, and these other estimators can appear to be quite biased, or utterly fail due to the boundary problem, when the OIPPMM is the true data-generating process. In addition, the OIPPMM provides a solution to the boundary problem, by labelling any mixture components on the boundary instead as one-inflation.
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http://dx.doi.org/10.1002/bimj.201800095 | DOI Listing |
Bioinformatics
January 2024
Department of Biostatistics, City University of Hong Kong, Tat Chee Avenue, Hong Kong, China.
Motivation: The utilization of single-cell bisulfite sequencing (scBS-seq) methods allows for precise analysis of DNA methylation patterns at the individual cell level, enabling the identification of rare populations, revealing cell-specific epigenetic changes, and improving differential methylation analysis. Nonetheless, the presence of sparse data and an overabundance of zeros and ones, attributed to limited sequencing depth and coverage, frequently results in reduced precision accuracy during the process of differential methylation detection using scBS-seq. Consequently, there is a pressing demand for an innovative differential methylation analysis approach that effectively tackles these data characteristics and enhances recognition accuracy.
View Article and Find Full Text PDFBMJ Open
October 2023
University of Cologne, Faculty of Medicine and University Hospital Cologne, Institute of Medical Sociology, Health Services Research and Rehabilitation Science, Chair of Health Services Research, Cologne, Germany.
Objectives: The rate of outpatient therapeutic curettage is lower in Germany than in other countries, although there are no differences in patient safety between outpatient and inpatient management. In this context, outpatient surgery is economically advantageous and efficient. This study aims to identify organisational and regional factors that determine the rate of outpatient curettage in German hospitals.
View Article and Find Full Text PDFHealth Qual Life Outcomes
March 2022
Faculty of Nursing, University of Calgary, Professional Faculties Building, 2500 University Drive NW, Calgary, AB, T2N 1N4, Canada.
Background: Nurses are known to have negative health outcomes related to their work. While it is acknowledged that nursing work is associated with things like back injuries and burnout, there is limited evidence as to what factors in the work environment contribute to these issues.
Purpose: The aims of this study were to assess how Licensed Practical Nurses (LPNs) report their Health-related quality of life (HRQoL), and how nurses' health is impacted by their work environment.
Biom J
November 2019
Department of Economics, University of Manitoba, Winnipeg, Manitoba, Canada.
Cad Saude Publica
October 2016
Universidade de São Paulo, São Paulo, Brasil.
Budget Impact Analyses require a set of essential information on health technology innovation, including expected rates of adoption. There is an absence of studies investigating trends, magnitude of budgetary effects and determinants of diffusion rates for health technology innovations worldwide during the last decades. The present study proposes a pilot assessment on main determinants influencing diffusion rates of pharmaceutical innovations within the Brazilian Unified National Health System (SUS).
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