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PREVALENCE OF COMORBIDITIES IN PATIENTS WITH CHAGASIC MEGAESOPHAGUS.
Arq Gastroenterol
November 2023
Hospital das Clínicas da Universidade Federal de Goiás, Divisão de Gastroenterologia, Goiânia, GO, Brasil.
•The study investigated the prevalence of certain comorbidities in patients with Chagas megaoesophagus compared to those without the condition, aiming to determine whether it serves as a protective or risk factor. •In the general group (546 patients), the three most prevalent comorbidities were hypertension (44.3%), dyslipidaemia (17.
View Article and Find Full Text PDFFrequency of Human Papillomavirus Detection in Chagasic Megaesophagus Associated or Not with Esophageal Squamous Cell Carcinoma.
Pathobiology
January 2022
Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos, Brazil.
Background: Chagasic megaesophagus (CM) as well as the presence of human papillomavirus (HPV) has been reported as etiological factors for esophageal squamous cell carcinoma (ESCC).
Objective: We assessed the prevalence of HPV DNA in a series of ESCCs associated or not with CM. Data obtained were further correlated to the pathological and clinical data of affected individuals.
Peroral endoscopic myotomy (POEM): a comparative study between Chagasic and idiopathic achalasia.
Endosc Int Open
April 2020
Gastrointestinal Endoscopy Unit, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Achalasia can be classified as either primary (idiopathic) achalasia or secondary achalasia, which is a consequence of another systemic disease. Peroral endoscopic myotomy (POEM) is an effective and safe treatment for achalasia. We evaluated the efficacy and safety of POEM in patients with Chagasic achalasia compared to idiopathic achalasia.
View Article and Find Full Text PDFSuprahyoid Muscle Activity in Patients with Chagasic Megaesophagus.
Sci Rep
December 2019
Postgraduate Program in Health Sciences, Health Sciences Center, State University of Maringá, Maringá, PR, Brazil.
The objective of this investigation was to evaluate the activity of the suprahyoid musculature during swallowing and to correlate the findings with the degree of megaesophagus, oral and pharyngeal videofluoroscopy and esophageal manometry in patients with achalasia caused by Chagas' disease. Twenty-nine patients with positive serology for Trypanosoma cruzi and dysphagia (Chagas' disease group) and 29 individuals matched by sex and age (control group) participated in the study. Surface electromyography of the suprahyoid musculature and videofluoroscopy during swallowing of paste and liquid consistencies were performed.
View Article and Find Full Text PDFChagasic Megaesophagus-Associated Carcinoma: Clinical Pattern and Outcomes.
J Glob Oncol
August 2019
State University of Campinas, Campinas, Brazil.
Purpose: Approximately 4% to 10% of patients diagnosed with Chagas-induced megaesophagus disease develop esophageal carcinoma. However, the natural history and clinical pattern of this entity are not well described.
Methods: Herein, we retrospectively analyzed 593 patients with esophageal carcinoma treated at a single Brazilian institution.
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