Central retinal venous occlusion in a child with hyperhomocysteinemia: A case report.

Rationale: To report a rare case of 8-year-old girl patient with central retinal venous occlusion (CRVO) with hyperhomocysteinemia.

Patient Concerns: The patient had a 2-year history on painless visual loss in the left eye.

Diagnoses: All examination results were within normal limits except plasma homocysteine (HCY). Fluorescein angiography (FA) confirmed peripheral capillary non-perfusion (CNP) in the left eye, and OCT showed macular edema. The girl patient was diagnosed as CRVO.

Interventions: Based on all of the test results, laser photocoagulation was performed at peripheral capillary non-perfusion (NP). Ranibizumab was injected into virtreous cavity to reduce the macular edema. Oral folic acid, vitamin B12, and vitamin B6 were performed to the girl.

Outcomes: After 13 months, the girl visual acuity recovered to 20/100 in the left eye.

Lessons: All eye examinations should be performed in young patients, and they should undergo treatments immediately after is diagnosed as CRVO.