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Amyotrophic lateral sclerosis in a patient with chronic lymphocytic leukaemia and drug related sarcoid-like reaction.
BMC Neurol
January 2025
Department of Neurology, Wessex Neurological Centre, University Hospital Southampton, Southampton, UK.
Sarcoid-like reaction is an immunological reaction that can affect lymph nodes and organs but does not meet the diagnostic criteria for systemic sarcoidosis. Anti-CD20 auto-antibodies have been reported to be responsible for such reactions. There are several reported associations between Chronic lymphocytic leukaemia (CLL), Amyotrophic lateral sclerosis (ALS) and Sarcoid-like reactions (SLR).
View Article and Find Full Text PDFC5 complement inhibition versus FcRn modulation in generalised myasthenia gravis.
J Neurol Neurosurg Psychiatry
January 2025
Department of Neurology, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany
Background: Myasthenia gravis (MG) is an autoimmune disorder affecting neuromuscular junctions, leading to fluctuating muscle weakness. While many patients respond well to standard immunosuppression, a substantial subgroup faces ongoing disease activity. Emerging treatments such as complement factor C5 inhibition (C5IT) and neonatal Fc receptor (FcRn) antagonism hold promise for these patients.
View Article and Find Full Text PDFHeavy Metal Accumulation (Cd, As, Zn, Cu, Cr) in Hair and Bones of Small Mammal Prey of the Sentinel Species Common Genet () in an Anthropogenic Environment of Edough Mountain Forest, Northeastern Algeria.
Animals (Basel)
January 2025
Engineering of Mineral Resources, Materials and Environment Department, North University Centre of Baia Mare, Technical University of Cluj-Napoca, 430083 Baia Mare, Romania.
Heavy metal pollution has complex impacts on terrestrial ecosystems, affecting biodiversity, trophic relationships, species health, and the quality of natural resources. This study aims to validate a non-invasive method for detecting heavy metals (Cd, As, Zn, Cu, Cr) in micromammalian prey, which constitute the primary diet of the common genet (), a mesocarnivore sensitive to habitat degradation. By focusing on prey remains (hair and bones) rather than entire fecal samples, this approach leverages the genet's selective feeding habits to assess the bioaccumulation of contaminants in its preferred prey.
View Article and Find Full Text PDFBio-concentration of hazardous metals in migrant shorebirds in a key conservation reserve and adjoining areas on the west coast of India.
Ecotoxicol Environ Saf
January 2025
Department of Biology, United Arab Emirates University, Al Ain 15551, United Arab Emirates; Department of Science, The Natural History Museum, Cromwell Road, South Kensington, London SW7 5BD, UK. Electronic address:
Heavy metal pollution is a growing environmental concern as it causes the degradation of wetlands by affecting the organisms at different trophic levels. Shorebirds typically feed on benthic invertebrates including polychaete worms, crustaceans and molluscs. Thus, the assessment of bioconcentration of heavy metals in shorebirds provides an insight into the extent of bioaccumulation of these hazardous metals in the upper trophic levels.
View Article and Find Full Text PDF10-Years of imagery from a cabled-observatory reveals a decreasing trend in coastal fish biodiversity.
Sci Total Environ
January 2025
SARTI Research Group, Electronic Department, Universitat Politècnica de Catalunya (UPC), Vilanova i la Geltrú, Spain.
Monitoring the effects of climate change and other multi-years processes on coastal ecosystems require long-term datasets that may extend into decades. One tool to achieve this are cabled seafloor observatories that can collect continual streams of environmental and biological data as long as the equipment is maintained. Here, we used 10-years of time-lapse images (every 30 mins) from the OBSEA seafloor cabled observatory located at 20 m depth, four km offshore from Vilanova i la Geltrú (Spain) coast, to characterize temporal trends in fish community dynamics.
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