AI Article Synopsis
- Recent studies indicate that pasireotide might be effective for certain aggressive prolactinomas, especially those resistant to dopamine treatments.
- Two previously published cases were reviewed, along with an additional case of a poorly differentiated plurihormonal adenoma.
- This adenoma was notably positive for PIT-1 and showed moderate SSTR2 and intense SSTR5 expression, and it was successfully treated with a monthly dose of PAS-LAR 40 mg.
Article Abstract
Recent publications suggested that pasireotide could be a good therapeutic option in some dopamine-resistant or aggressive prolactinomas. We discussed the two published cases and describe another case of poorly differentiated plurihormonal PIT-1-positive adenoma with moderate SSTR2 expression and intense STTR5 expression successfully treated with PAS-LAR 40 mg/month.
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| http://dx.doi.org/10.1530/EJE-19-0359 | DOI Listing |
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