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Calcitriol Concentration in the Early Phase of Myocardial Infarction and Its Relation to Left Ventricular Ejection Fraction.
Metabolites
December 2024
Department of Cardiology, Pomeranian Medical University in Szczecin, 70-111 Szczecin, Poland.
Vitamin D deficiency is one of the most common metabolic disorders in the European population. A low level of 25-OH vitamin D3 is related to an elevated risk of myocardial infarction (MI). The aim of our study was to examine the relationship between calcidiol and calcitriol serum concentration and left ventricular ejection fraction early after interventional treatment for acute coronary syndrome.
View Article and Find Full Text PDFWastewater-based monitoring of antipyretics use during COVID-19 outbreak in China and its associated ecological risks.
Environ Res
December 2024
Laboratory of Earth Surface Processes, College of Urban and Environmental Sciences, Peking University, 100871, Beijing, PR China. Electronic address:
At the end of 2022, a sudden policy shift in China triggered an unprecedented COVID-19 outbreak that led to a dramatic increase in the consumption of antipyretics. In this study, the occurrence of the two most commonly used antipyretics (ibuprofen and paracetamol) and their metabolites were analyzed in the wastewater of nine major cities in China, covering the periods before, during, and after the policy change. The remarkable surge after the policy change for ibuprofen and paracetamol reached 67 times (in Nanning) and 311 times (in Lanzhou) compared to pre-pandemic levels, respectively.
View Article and Find Full Text PDFDual Antiplatelet Treatment up to 72 Hours After Ischemic Stroke Stratified by Risk Profile: A Post Hoc Analysis.
Stroke
January 2025
Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.Z., X.W., Y.G., W.C., H.Y., T.W., Y.Y., Q.Z., M.W., J.J., C.W., Yongjun Wang, Yilong Wang, Y.P.).
Background: Risk profile of recurrence may influence the effect of antiplatelet therapy. This study aimed to evaluate the efficacy and safety of clopidogrel-aspirin initiated within 72 hours after symptom onset for acute mild stroke or high-risk transient ischemic attack stratified by risk profile.
Methods: This is a secondary post hoc analysis of the INSPIRES (Intensive Statin and Antiplatelet Therapy for Acute High-risk Intracranial or Extracranial Atherosclerosis) randomized clinical trial that enrolled patients 35 to 80 years old with acute mild ischemic stroke or high-risk transient ischemic attack between 2018 and 2022.
Effects of physical exercise on cardio-respiratory health of young adults during short-term exposure to varying air pollution levels.
BMC Public Health
December 2024
School of Exercise and Health, Shanghai University of Sport, Yangpu District Qingyuan Huan Road 650, Shanghai, 200438, China.
Background: Air pollution (AP) has become a substantial environmental issue affecting human cardiorespiratory health. Physical exercise (PE) is widely accepted to promote cardiorespiratory health. There is a paucity of research on the point at which the level of polluted environment engaged in PE could be used as a preventive approach to compensate for the damages of AP.
View Article and Find Full Text PDFPrevalence and risk factors of frailty in older patients with coronary heart disease: A systematic review and meta-analysis.
Arch Gerontol Geriatr
December 2024
Hospital of Chengdu University of Traditional Chinese Medicine, 610075, PR China. Electronic address:
Objective: To quantitatively synthesise evidence on the prevalence of and risk factors of frailty in older patients with coronary heart disease.
Methods: Nine electronic databases were searched from the inception to July 20th 2024. Random-effects model was performed to calculate to estimate the prevalence of frailty in older patients with coronary heart disease.
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