Skeletal Muscle Atrophy: Discovery of Mechanisms and Potential Therapies.

Physiology (Bethesda)

Departments of Internal Medicine and Molecular Physiology and Biophysics, and the Fraternal Order of Eagles Diabetes Research Center, Roy J. and Lucille A. Carver College of Medicine, The University of Iowa, Iowa City, Iowa.

Published: July 2019

Skeletal muscle atrophy proceeds through a complex molecular signaling network that is just beginning to be understood. Here, we discuss examples of recently identified molecular mechanisms of muscle atrophy and how they highlight an immense need and opportunity for focused biochemical investigations and further unbiased discovery work.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863373PMC
http://dx.doi.org/10.1152/physiol.00003.2019DOI Listing

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