Zeaxanthin dipalmitate () and two zeaxanthin dipalmitate derivatives, including one new compound (), were obtained from wolfberry [the fruit of L. (Solanaceae)]. Their structures were unambiguously elucidated by spectroscopic analyses. Compound is isolated from the genus for the first time, and its 1D/2D NMR data are firstly reported. All the compounds belong to carotenoids which are a kind of major bioactive constituents in wolfberry and are also responsible for wolfberry's red color.
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http://dx.doi.org/10.1080/10286020.2019.1621855 | DOI Listing |
Int J Biol Macromol
November 2024
School of Pharmacy, Ningxia Medical University, Yinchuan, Ningxia, China; Ningxia Key Laboratory of Drug Development and Generic Drug Research, Yinchuan, Ningxia, China. Electronic address:
The emulsion gel composed of proteins and polysaccharides exhibits significant potential as a targeted delivery system for bioactives in the gastrointestinal tract. In this study, a composite emulsion was prepared by using sodium caseinate (NaCas) and gellan gum (GG), which was subsequently crosslinked with transglutaminase (TG), glucono-δ-lactone (GDL), and calcium ions (Ca) to form emulsion gels. The physicochemical properties of the NaCas/GG emulsion gels were characterized to verify the effects of zeaxanthin dipalmitate encapsulation and protection, and a possible mechanism was discussed.
View Article and Find Full Text PDFPLoS One
May 2024
Key Laboratory of CNS Regeneration (Jinan University)-Ministry of Education, Guangdong-Hong Kong-Macau Institute of CNS Regeneration, Guangdong Key Laboratory of Non-Human Primate Research, Jinan University, Guangzhou, Guangdong Province, China.
Zeaxanthin dipalmitate (ZD) is a chemical extracted from wolfberry that protects degenerated photoreceptors in mouse retina. However, the pure ZD is expensive and hard to produce. In this study, we developed a method to enrich ZD from wolfberry on a production line and examined whether it may also protect the degenerated mouse retina.
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November 2022
School of Food & Wine, Ningxia University, Yinchuan 750021, China.
Goji berry (Lycium barbarum L., LBL) is a good source of carotenoids, while the bioaccessibility of various types of LBL carotenoids has not been explored. In the study, eight carotenoids, three carotenoid esters and two carotenoid glycosylated derivatives were identified by a non−targeted metabolomics approach.
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November 2022
Institute of Wolfberry Engineering and Technology, Ningxia Academy of Agriculture and Forestry Sciences, Yinchuan 750004, China.
In the present study, protein-polysaccharide Maillard conjugates were used as novel emulsifiers and bioactive carriers. Effects and potential mechanisms of zeaxanthin dipalmitate (ZD)-enriched emulsion stabilized with whey protein isolate (WPI)-gum Arabic (GA) conjugate (WPI-GA-ZD) and ZD-free emulsion (WPI-GA) on gut microbiota and inflammation were investigated using a model of dextran sulfate sodium (DSS)-induced colitis in mice. As a result, supplementation with WPI-GA and WPI-GA-ZD improved the serum physiological and biochemical indicators, decreased the expression of pro-inflammatory cytokines and related mRNA, as well as increased the tight junction proteins to a certain extent.
View Article and Find Full Text PDFFront Chem
November 2022
Institute of TCM International Standardization, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Carotenoids from fruits have possessed pharmacological efficacy against eye diseases, cardiovascular disorders, cancer, and benign prostatic hyperplasia. However, the efficient extraction, rapid characterization and activities evaluation of carotenoids remains a challenge. To concentrate and characterize carotenoids, we have developed ultrasound-assisted extraction methods with different deep eutectic solvents (DESs) and analyzed carotenoids by ultra-performance convergence chromatography coupled with photo diode array detector and quadrupole time-of-flight mass spectrometry (UPC-PDA-Q-TOF-MS).
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