Acid-base equilibrium, glycolytic parameters, electrophoretic mobility and hemoglobin oxygen affinity in blood of rats exposed to hyperbaric oxygenation were measured. The animals were kept at 2026 kPa for 15, 30 or 60 min. It was found that the short-term oxygenation led to changes in acid-base equilibrium, then to biochemical changes in plasma and erythrocytes and, consequently, to a higher oxygen-binding ability of hemoglobin. The increased hemoglobin oxygen affinity was significantly stable and persisted for a certain period of time in the normal atmosphere. The experimental data demonstrated that most blood parameters taken under study varied in a different manner, depending on the time during which the animals were exposed to oxygen.

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