Clinical efficiency of the antiarrhythmic agent palpitin used for the treatment of ventricular and supraventricular extra-systole was assessed in 94 coronary patients, using Holter's ECG monitoring, electrophysiologic studies and rheographic control; reliable evidence in favor of the drug high antiarrhythmic efficiency was obtained.
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J Pathol Clin Res
January 2025
Department of Urology, University of Duisburg-Essen, Essen, Germany.
Distinct molecular subtypes of muscle-invasive bladder cancer (MIBC) may show different platinum sensitivities. Currently available data were mostly generated at transcriptome level and have limited comparability to each other. We aimed to determine the platinum sensitivity of molecular subtypes by using the protein expression-based Lund Taxonomy.
View Article and Find Full Text PDFCurr Med Chem
January 2025
Shree S K Patel College of Pharmaceutical Education and Research, Ganpat University, Mahesana, Gujarat, 384012, India.
Therapeutic hurdles persist in the fight against lung cancer, although it is a leading cause of cancer-related deaths worldwide. Results are still not up to par, even with the best efforts of conventional medicine, thus new avenues of investigation are required. Examining how immunotherapy, precision medicine, and AI are being used to manage lung cancer, this review shows how these tools can change the game for patients and increase their chances of survival.
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January 2025
Department of Electronics & Communication Engineering, Jaypee University of Information Technology, Solan, H.P., India.
A planktonic population of bacteria can form a biofilm by adhesion and colonization. Proteins known as "adhesins" can bind to certain environmental structures, such as sugars, which will cause the bacteria to attach to the substrate. Quorum sensing is used to establish the population is dense enough to form a biofilm.
View Article and Find Full Text PDFFront Child Adolesc Psychiatry
October 2022
Department of Health Sciences, University of York, York, United Kingdom.
In 2015, The Alleviating Specific Phobias Experienced by Children Trial (ASPECT) was commissioned by the National Institute for Health and Care Research (NIHR) to compare the clinical and cost-effectiveness of multi-session Cognitive Behavioral Therapy (CBT) for specific phobias in children and young people (CYP) (aged 7-16), with a briefer variant called One Session Treatment (OST). From 2016 to 2020, ASPECT recruited = 274 CYP with specific phobias and their families from across England, including 26 Child and Adolescent Mental Health Services (CAMHS) centres, three voluntary sector centers and one University-based wellbeing service. Whilst the trial successfully reached its recruitment target, the challenges experienced in its delivery highlight the difficulties of embedding child and adolescent research into clinical settings and routine practice.
View Article and Find Full Text PDFClin Interv Aging
January 2025
Department of Orthopedics, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, 200072, People's Republic of China.
Purpose: Shoulder arthroscopic repair of rotator cuff tears with simultaneous treatment of lesions of the long head of the biceps tendon has become increasingly accepted. However, the clinical outcomes between tenotomy and tenodesis remain unclear. This study aimed to compare the efficacy of tenotomy and tenodesis combined with rotator cuff repair in elderly patients with medium-to-massive rotator cuff tears.
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