(,)-3-Methyl-2,5-bis-(4-methyl-benzyl-idene)cyclo-penta-none: synthesis, characterization, Hirshfeld surface analysis and anti-bacterial activity.

Acta Crystallogr E Crystallogr Commun

Université de Rennes 1, Institut des Sciences Chimiques de Rennes, CNRS UMR, 6226, Avenue du Général Leclerc, 35042 Rennes Cedex, France.

Published: April 2019

The title compound, (,)-3-methyl-2,5-bis-(4-methyl-benzyl-idene)cyclo-penta-none (MBMCP), CHO, was obtained by Claisen-Schmidt condensation of 4-methyl-benzaldehyde with 3-methyl-cyclo-penta-none in good yield. The structure of MBMCP was studied using UV, FT-IR and Raman spectroscopy, single-crystal X-ray diffraction (XRD) measurements, and H and C nuclear magnetic resonance (NMR) spectroscopy. The mol-ecular structure of MBMCP is fully extended in the , configuration. C-H⋯π stacking inter-actions play a significant role in the stabilization of the mol-ecular packing. Hirshfeld surface analysis was used to qu-antify the non-covalent inter-actions in the crystal lattice. Microbiological studies were performed to investigate the anti-microbial activity of this new product.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509686PMC
http://dx.doi.org/10.1107/S2056989019003827DOI Listing

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