AI Article Synopsis
- The study aimed to investigate salivary cortisol levels in patients with oral lichen planus (OLP) compared to healthy controls, focusing on stress-related cortisol changes.
- It included seven reticular (non-symptomatic) OLP patients, eight atrophic/erosive (symptomatic) OLP patients, and nine healthy individuals, testing the hypothesis that symptomatic patients would show higher cortisol levels.
- Results indicated no significant differences in salivary cortisol levels between OLP patients and healthy controls, suggesting the need for further research with a larger sample size to explore the link between OLP and stress.
Article Abstract
It is known that cortisol level increases in stress situations. The aim of the study was to measure the levels of salivary cortisol in patients with oral lichen planus (OLP) and healthy controls. This was a case-control pilot study which included seven patients with reticular (non-symptomatic) OLP, eight patients with atrophic/erosive (symptomatic) OLP, and nine healthy controls. We hypothesized that patients with an atrophic/erosive type of OLP have higher levels of cortisol compared to patients with the reticular type of OLP and healthy controls. In each participant, unstimulated saliva was collected in order to determine cortisol levels by using commercially available ELISA kit. Our results have shown no differences between levels of salivary cortisol in OLP patients and healthy controls. We can conclude that further research with a larger number of OLP patients is needed to determine the correlation between OLP and stress.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631431 | PMC |
| http://dx.doi.org/10.3390/dj7020059 | DOI Listing |
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