Coinfection mechanism is a common interacting mode between multiple diseases in real spreading processes, where the diseases mutually increase their susceptibility, and has aroused widespread studies in network science. We use the bond percolation theory to characterize the coinfection model under two self-awareness control strategies, including immunization strategy and quarantine strategy, and to study the impacts of the synergy effect and control strategies on cooperative epidemics. We find that strengthening the synergy effect can reduce the epidemic threshold and enhance the outbreak size of coinfected networks. On Erdős-Rényi networks, the synergy effect will induce a crossover phenomenon of phase transition, i.e., make the type of phase transition from being continuous to discontinuous. Self-awareness control strategies play a non-negligible role in suppressing cooperative epidemics. In particular, increasing immunization or the quarantine rate can enhance the epidemic threshold and reduce the outbreak size of cooperative epidemics, and lead to a crossover phenomenon of transition from being discontinuous to continuous. The impact of quarantine strategy on cooperative epidemics is more significant than the immunization strategy, which is verified on scale-free networks.
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http://dx.doi.org/10.1063/1.5063960 | DOI Listing |
Learn Health Syst
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Department of Biostatistics, Epidemiology and Informatics University of Pennsylvania Perelman School of Medicine Philadelphia Pennsylvania USA.
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View Article and Find Full Text PDFJ Extracell Vesicles
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Laboratory of Experimental Clinical Chemistry, Laboratory Specialized Diagnostics & Research, Department of Laboratory Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Breast Cancer Res
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Department of Medicine (Hematology/Oncology), School of Medicine, University of California San Francisco, 1450 Third St, San Francisco, CA, 94158, USA.
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View Article and Find Full Text PDFJCO Glob Oncol
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Latin American Cooperative Oncology Group, Porto Alegre, Brazil.
Purpose: The availability of drugs and national public policies for patients with rare cancers, including sarcomas, varies in different parts of the world.
Methods: In this manuscript, we have conducted a comprehensive analysis to evaluate rare cancer policies in Latin American countries' national policy documents. Additionally, we have reviewed the approvals for sarcoma drugs in selected Latin American countries and compared them with US Food and Drug Administration (FDA) and European Medicines Agency (EMA) approvals.
Alzheimers Dement
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Virginia Center on Aging, College of Health Professions, Virginia Commonwealth University, Richmond, Virginia, USA.
Introduction: The Virginia Memory Project (VMP) is a statewide epidemiological registry for Alzheimer's disease and related disorders (ADRD) and other neurodegenerative conditions. It aims to support dementia research, policy, and care by leveraging the Centers for Disease Control (CDC) Healthy Brain Initiative (HBI) Roadmap.
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